Abstract：Objective: To analyze the long-term prognosis and influencing factors of regular and irregular resection of single small liver cancer. Methods: 89 patients with single small liver cancer who treated from May 2010 to May 2013 in our hospital, according to random number table method, those patients were divided into 40 cases of A group and 49 cases of B group,group A used regular resection and group B used irregular resection. The operation and complications in both groups were compared, and the influencing factors of long-term prognosis were analyzed. Results: The operation time, intraoperative blood loss, margin size and length of hospital stay in the irregular resection group were lower than those in the regular resection group (P<0.05). the total complication rate in the both groups was no significant difference (P>0.05). Univariate analysis showed that gender, age, Child-pugh grade, serum HbsAg, CGT, AEP, total bilirubin, ALT level, tumor margin, hepatic occlusion time, bleeding volume, and whether the rule was removed for 5 years were no significant difference in survival rate (P>0.05). there were significant differences in 5-year survival rates between different albumin levels, tumor size, tumor capsule, long-term smoking, and intraoperative blood transfusion (P<0.05). Cox regression analysis showed that tumor size and long-term smoking were independent risk factors for the prognosis of patients with single hepatocellular carcinoma, tumor envelope integrity and albumin levels were protective factors. Conclusion: The long-term prognosis of small hepatocellular carcinoma is related to various factors. Regular hepatectomy is not an independent prognostic factor, and the optimal operation should be selected clinically according to the tumor anatomical location and liver function reserve of patients.
黄凤德, 胥丹, 安志明, 谢田伟. 规则与非规则切除单发小肝癌的长期预后及影响因素分析[J]. 河北医学, 2019, 25(5): 811-815.
HUANG Fengde, XU Dan, AN Zhiming, et al. Analysis on Long-term Prognosis and Influencing Factors of Regular and Irregular Resection of Single Small Liver Cancer. HeBei Med, 2019, 25(5): 811-815.
2019, Vol. 25 
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