Abstract：Objective: To analyze the diagnostic value of single photon emission computed tomography-computed tomography (SPECT-CT) and magnetic resonance imaging (MRI) for osteoporotic vertebral compression fractures (OVCF). Methods: The clinical data of 82 patients with OVCF in our hospital from March 2016 to April 2018 were retrospectively analyzed. Among them, 67 cases were acute-phase fractures (disease course≤ 3 w) and 15 cases were subacute-phase fractures (disease course 4~12 w). The detection of responsible vertebral bodies by SPECT-CT and MRI was recorded in patients with acute-phase fractures and subacute-phase fractures, and 82 patients were given percutaneous kyphoplasty (PKP). The pain degree [visual analogue score (VAS)] in 82 patients were compared before operation and at 3d after operation. Results: A total of 83 vertebral bodies in 67 patients with acute OVCF were given PKP. Among them, MRI and SPECT-CT confirmed 82 responsible vertebral bodies, and Kappa value was 0.845 (P<0.001), and the consistency was extremely strong. 1 case (1.20%) was missed diagnosis and 1 case (14.29%) was misdiagnosed by SPECT-CT. 34 vertebral bodies in 15 patients with subacute OVCF were given PKP. Among them, MRI and SPECT-CT confirmed 29 responsible vertebral bodies, and Kappa value was 0.633 (P<0.001), and the consistency was high. 1 case (3.33%) was missed diagnosis and 1 case (33.33%) was misdiagnosed by SPECT-CT. At 3 d after operation, the VAS scores in 82 patients with OVCF were decreased compared with those before operation (P<0.05). Conclusions: SPECT-CT and MRI can confirm the responsible vertebral bodies of OVCF. When patients have MRI examination contraindications, SPECT-CT can be selected as the examination method for evaluating responsible vertebral bodies of OVCF.
2019, Vol. 25 
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