Abstract:Objective: To retrospectively analyze the MRI manifestations and related literature of 4 pathologically confirmed giant cell reparative granuloma of temporal bone in our hospital in recent 5 years, so as to improve the understanding of the disease and further improve the diagnostic accuracy of MRI. Methods: Four patients with giant cell reparative granuloma of the temporal bone diagnosed in our hospital in recent five years were collected. Two experienced doctors performed image analysis separately. The morphology, extent, signal, bone destruction, adjacent relationship and enhancement degree of the lesion were observed. Combined with the MRI manifestations and related literature of these four patients, some relative characteristics of the disease were summarized. Significant MRI findings. Results: The MRI findings of 4 cases were as follows: all lesions occurred in temporal bone, 1 case in left temporal bone, 3 cases in right temporal bone, unclear boundary and irregular shape. The lesions were mainly composed of mixed signal shadows with low signal intensity on T2WI. There were patchy long T1 long T2 cystic necrosis, hemoglobin deposition on short T1 and long T1 short T2. After enhancement, the lesions were unevenly enhanced (cystic change, hemorrhage and hemoglobin deposition on long T1 short T2). The heme-iron-containing area was not strengthened, and it was close to bone destruction. One case had right temporal bone mass and right middle ear mastoiditis. Two of the 4 cases were misdiagnosed as giant cell tumor of bone and chondrosarcoma before operation. Conclusion: Giant cell reparative granuloma may be considered if short T2-dominated, unevenly enhanced space occupying the temporal bone is near bone destruction, but it needs to be differentiated from giant cell tumors, chondrosarcomas, aneurysmal bone cysts and other diseases.