Abstract：Objective: To investigate the diagnostic value of conventional ultrasound(CUS),ultrasound elastography(UE) and fine needle aspiration cytology(FNA) in thyroid microcarcinoma.Methods:279 thyroid nodules confirmed by operation and pathology were retrospectively analyzed. The diagnostic criteria of thyroid cancer were greater than or equal to 4 scores of elastic score and Bethesda report system classification ≥Ⅴ, and the diagnostic sensitivity, specificity, positive predictive value, negative predictive value and correct rate were calculated respectively compared with the pathological gold standard.Result:Of the 279 nodules, 124 were malignant and 155 were benign; 121 were malignant and 158 were benign by CUS, 170 were malignant and 109 were benign by UE, 162 were malignant and 117 were benign by FNA,102 were malignant and 177 were benign by CUS+UE series,106 were malignant and 173 were benign by CUS+FNA series. The sensitivity of UE and FNA for diagnosing thyroid microcarcinoma was higher than that of CUS, while specificity and positive predictive value were lower than CUS, and the difference was statistically significant(P<0.05).The CUS+UE series specificity, correct rate, positive predictive value and Eugene index were higher than CUS, the difference was statistically significant (P<0.05). The CUS+ FNA series specificity and positive predictive value were higher than CUS, the difference was statistically significant (P<0.05).Conclusion:CUS, UE and FNA have certain deficiencies in the diagnosis of thyroid microcarcinoma. CUS+ UE series and CUS+ FNA series specificity is higher than CUS, which can improve the early diagnosis of thyroid microcarcinoma and has high clinical value. At the same time, CUS+UE series is superior to CUS+FNA series in terms of non-invasiveness and low cost, which is worthy of clinical promotion.
吴文瑛, 王晓岩, 赵丽, 李韬, 聂明辉, 常乾坤, 冯佩明. 常规超声和弹性成像及细针穿刺细胞学活检对甲状腺微小癌的诊断价值[J]. 河北医学, 2019, 25(3): 627-629.
WU Wenying, WANG Xiaoyan, ZHAO Li, et al. Diagnostic Value of Conventional Ultrasound and Elastography with Fine Needle Aspiration Cytology in Thyroid Microcarcinoma. HeBei Med, 2019, 25(3): 627-629.
2019, Vol. 25 
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