Abstract：Objective: To explore the clinical significance of the detection of PTH and Hcy in patients with the chronic kidney disease. Methods: 48 patients with chronic kidney disease (CKD) were divided into three groups: CKD stage 3, CKD stage 4 and CKD stage 5 according to the clinical diagnosis. PTH, Cys C, Hcy and Cr were detected in three groups, and the statistical analysis was conducted. Results: The levels of serum PTH, Cys C, Hcy and Cr in CKD stage 5 group were higher than those in CKD stage 4 and CKD stage 3 groups, the difference was statistically significant (P<0.05), but there was no significant difference between CKD stage 4 group and CKD stage 3 group in serum PTH, Cys C , Hcy and Cr levels (P>0.05 ). The positive rates of PTH in CKD stage 5 group, CKD stage 4 group and CKD stage 3 group were: 70.8%, 21.4%, 20%; The positive rates of Hcy in CKD stage 5 group, CKD stage 4 group and CKD stage 3 group were: 58.3%, 7.1%, 10% . PTH,Hcy,Cr and Cys C were positively correlated(R=0.505、0.855、0.788). Conclusion: The combined detection of PTH, Hcy and other indicators is helpful for the diagnosis and judgment of CKD patients, and provides accurate guidance for clinical diagnosis and treatment.
刘虹, 金娟, 周志凤, 张白银, 郑元杰, 陈正徐, 曹娟. 慢性肾脏病患者甲状旁腺激素同型半胱氨酸检测的临床意义[J]. 河北医学, 2019, 25(3): 577-579.
LIU Hong, JIN Juan, ZHOU Zhifeng, et al. Clinical Significance of Detection of Parathyroid Hormone and Homocysteine in Patients with Chronic Kidney Disease. HeBei Med, 2019, 25(3): 577-579.
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2019, Vol. 25 
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