Abstract：Objective: To study the current status and drug resistance of genital tract mycoplasma infections in patients with tubal infertility. Methods: 227 patients with tubal infertility who were admitted to the hospital from January 2015 to June 2017 were included in the infertility group. 100 healthy female volunteers were selected as the control group at the same time. The cervical secretions were collected for mycoplasma culture, identification and drug sensitivity test. Results: A total of 129 cases with genital tract mycoplasma infection were detected in 227 patients with tubal infertility, including 66 cases with Ureaplasma urealyticum infection, 38 cases with Mycoplasma hominis infection and 25 cases with Ureaplasma urealyticum and Mycoplasma hominis infections. The total genital tract mycoplasma infection rate in the infertility group was significantly higher than that in the control group (56.8% vs 14.0%) (χ2=51.746, P=0.000). Ureaplasma urealyticum was most sensitive to doxycycline and mycophencin, and the sensitivity rate was 93.9%. The drug resistance to clarithromycin was the highest, and the drug resistance rate was 56.1%. Mycoplasma hominis was most sensitive to tetracycline and doxycycline, and the sensitivity rate was 94.7%. The drug resistance to roxithromycin was the highest, and the resistance rate was 68.4%. Ureaplasma urealyticum and Mycoplasma hominis were most sensitive to doxycycline, and the sensitivity rate was 88.0%,. The drug resistance to azithromycin was the highest, and the resistance rate was 92.0%. Conclusion:. Ureaplasma urealyticum infection is the main part of genital tract mycoplasma infection, showing multi-drug resistance. The clinical treatment should be guided by results of drug sensitivity test.
王原媛, 周欣雨, 刘杨. 我院227例输卵管性不孕患者生殖道支原体感染及药敏结果分析[J]. 河北医学, 2019, 25(2): 337-340.
WANG Yuanyuan, et al. Genital Tract Mycoplasma Infection in 227 Patients with Tubal Infertility in our Hospital and Results of Drug Sensitivity Test. HeBei Med, 2019, 25(2): 337-340.
2019, Vol. 25 
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