Abstract：Objective: To investigate the efficacy of laparoscopic myomectomy for uterine leiomyoma and the influence on anti-Mullerian hormone (AMH) and cervical microcirculation. Methods: 95 patients with uterine leiomyoma admitted to our hospital from February 2015 to March 2018 were selected as the study subjects. They were randomly divided into observation group (n=50) and control group (n=45). The control group was treated with open hysteromyomectomy, while the observation group was treated with laparoscopic hysteromyomectomy. The operation time, hospitalization time, bleeding volume, recovery time of gastrointestinal tract, antimullerian hormone, follicle stimulating hormone (FSH), blood perfusion, capillary diameter, loop shape integral, blood flow integral and postoperative complications were compared between the two groups. Results: After treatment, operation time, hospital stay, blood loss and postoperative gastrointestinal recovery time of the observation group were significantly lower than those of the control group (P<0.05). There was no significant difference in AMH and FSH before treatment between the two groups. After treatment, AMH level in the observation group was significantly higher than that in the control group, and FSH level was lower than that in the control group (P<0.05). There was no significant difference between the two groups in the blood perfusion before treatment, capillary vessel diameter, and tubular loop shape integral and blood flow integral of nail fold microcirculation. After treatment, the shape integral and blood flow integral of the tubule loop in the blood perfusion and nail fold microcirculation were significantly lower in the observation group than in the control group, and the capillary diameter was higher than that in the control group (P<0.05). During the treatment, the total incidence of complications in the observation group was 4.00%, significantly lower than 22.22% in the control group (P<0.05). Conclusion: Laparoscopic myomectomy in patients with uterine leiomyoma has a significant effect, and has little effect on AMH level and cervical microcirculation. It is worth popularizing and applying.
[1] 王瑞敏,侯懿.腹腔镜子宫肌瘤剔除术与传统开腹手术治疗子宫肌瘤的临床疗效比较[J].重庆医学,2014,43(7):852~853. [2] Donnez J, Dolmans M M. Uterine fibroid management: from the present to the future[J]. Human Reproduction Update,2016,22(6):665~686. [3] 王佳佳,徐时方.腹腔镜超声在腹腔镜子宫肌瘤剔除术中的应用价值[J].现代妇产科进展,2015,24(3):216~219. [4] 王世阆.子宫肌瘤的鉴别诊断[J].实用妇产科杂志,2007,(12):709~710. [5] Olejek A, Olszakwasik K, Czerwinskabednarska A. Long-term intermittent pharmacological therapy of uterine fibroids-a possibility to avoid hysterectomy and its negative consequences[J]. Przeglad Menopauzalny = Menopause Review,2016,15(1):48~51. [6] 王亚光,吕维富,李兵.子宫肌瘤子宫动脉栓塞术中瘤体与卵巢血供的相关性及临床观察[J].介入放射学杂志,2015,24(3):206~209. [7] Spies J B. Current role of uterine artery embolization in the management of uterine fibroids[J]. Clinical Obstetrics & Gynecology,2016,59(1):93~102. [8] 蒋珊珊,胡京辉,沈燕.腹腔镜下子宫肌瘤剔除术联合术前应用促性腺激素释放激素激动剂治疗大子宫肌瘤的疗效观察[J].中国内镜杂志,2017,23(5):1~4. [9] Ni B, He F Z, Pan Y T, et al. Using shapes correlation for active contour segmentation of uterine fibroid ultrasound images in computer-aided therapy[J]. Applied Mathematics:A Journal of Chinese Universities,2016,31(1):37~52. [10] 徐珂,肖雁冰.MURU对子宫肌瘤患者子宫血流动力学和卵巢功能的影响[J].东南大学学报(医学版),2017,36(3):369~372.
2019, Vol. 25 
冀公网安备13080202000677号