Abstract:Objective: To explore the value of real-time two-dimensional quantitative shear wave elastography (E-imaging) in evaluating the degree of liver fibrosis. Method: A total of 153 patients with clinically confirmed hepatic fibrosis were enrolled. All patients were examined by E-imaging. According to the pathological results of liver puncture, all patients were divided into four groups: hepatic fibrosis stage 1 group (S1 group), hepatic fibrosis stage 2 group (S2 group), hepatic fibrosis stage 3 group (S3 group) and hepatic fibrosis stage 4 group (S4 group), and 80 normal persons in the same period were selected as control group. The difference of Young's modulus of elasticity between groups was compared. Results: The case group was compared with the control group. The control group was significantly lower than that of hepatic fibrosis group (P<0.05). The Young's modulus of elasticity in case group was significantly higher than that in control group< S1 group< S2 group< S3 group< S4 group (P<0.05). Conclusion: Real-time two-dimensional quantitative shear wave elastography (E-imaging) can provide objective criteria for evaluating the grading of liver fibrosis.