Abstract：Objective: Specific IgE (sIgE) in serum of patients with Chronic urticaria (CU) were detected to provide basis for the prevention of the disease. Methods: The serum sIgE of 300 cases with spontaneous chronic urticaria were detected by Medwiss allergen detection system imported from Germany. Results: Among the 300 patients, 193 cases were positive for sIgE ,with a positive rate of 64.3%. The top three inhaled allergens were dust mite, grass combination, mold combination. The top three food allergens were cashew nuts, amaranth, milk.Compared with the male group and the female group, there was no difference in the total sIgE detection rate and the sIgE detection rate of inhalation and food(P>0.05). There was no difference between the total sIgE detection rate and the inhalation sIgE detection rate between the children group and adults group(P>0.05),while the food sIgE detection rate of children group was higher than that of the adult group(P<0.05) . Conclusion: The occurrence of spontaneous CU is related to serum sIgE, allergen detection is helpful for the treatment and prevention of patients with spontaneous chronic urticaria.
2019, Vol. 25 
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