Abstract：Objective: To study the clinical value of optical coherence tomography (OCT) in the diagnosis of central serous chorioretinopathy (CSC). Methods: 98 patients suspected as CSC admitted to our hospital from September 2015 to March 2018 were retrospectively analyzed. Fluorescein fundus angiography (FFA) and OCT were performed at the same time. The results of FFA examination were taken as references by CSC, and the diagnostic efficacy and consistency analysis of the two examination methods were compared, and the FFA leakage point distribution and OCT images at leakage point were observed when patients were diagnosed as CSC. Results: Among the 98 patients, 85 cases (86.73%) were diagnosed as CSC by FFA, and 82 cases (83.67%) were diagnosed as CSC by OCT, and there was no significant difference between the two methods (P>0.05), and the sensitivity, specificity and accuracy rate of the two diagnostic methods were 96.47%, 76.92% and 93.88%, and the diagnostic consistency was good (Kappa>0.7). The number of FFA fluorescence leakage points was 104 among 85 patients, mainly 87 cases (88.78%) in one leakage point, and the leakage point morphology was mostly ink-spot type in 61 cases (70.11%). Among 82 cases of affected eyes, there were abnormalities of FFA fluorescence leakage point in OCT images, including 21 eyes (25.61%) of PED, 2 eyes (9.52%) of defects in RPE, 28 eyes (34.15%) of small polypoid in RPE and33 eyes (40.24%) of rough RPE. OCT was used in 82cases of affected eyes without FFA leakage points, and there were abnormal changes in RPE layer in 7 cases of images, including 2 eyes (28.57%) of PED, 1 eye (14.29%) of RPE defect, 2 eyes (28.57%) of small polypoid in RPE and 3 eyes (42.86%) of rough RPE. Conclusions: There were fluorescent leakage points in all patients diagnosed by CSC using FFA, and abnormal changes of RPE were found in both fluorescent leakage points and non-fluorescent leakage points of patients diagnosed by CSC using OCT, which were in good agreement with the results of FFA.
王丽晶, 胡桂荣, 石玲, 杜晶, 杜颖. 中心性浆液性脉络膜视网膜病变使用OCT诊断价值[J]. 河北医学, 2019, 25(12): 2028-2032.
WANG Lijing, HU Guirong, SHI Ling, et al. Diagnostic Value of OCT in Central Serous Chorioretinopathy. HeBei Med, 2019, 25(12): 2028-2032.
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2019, Vol. 25 
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