Abstract:Objective: To explore the effects of YAG laser peripheral iridotomy on intraocular pressure after refractory glaucoma treatment. Methods: The treatment data of 79 patients with refractory glaucoma in our hospital from January 2016 to January 2017 were retrospectively analyzed. Study group (n=40, 45 eyes) was given YAG laser peripheral iridotomy, and control group ( n=39, 43 eyes) was given routine peripheral iridotomy. The intraocular pressure, visual acuity, peripheral anterior chamber depth and anterior chamber angle before and after surgery, occurrence of postoperative complications and surgical success rate were compared between the two groups. Results: Postoperative intraocular pressure was significantly decreased in the two groups (P<0.05), and the index after operation in study group was significantly lower than that in control group (P<0.05). The changes of visual acuity in study group after surgery was significantly ,lower than that in control group (P<0.05). The anterior chamber depth and anterior chamber angle in the two groups was significantly improved after surgery compared with that before surgery (P<0.05), and the index in study group after surgery was significantly higher than that in control group (P<0.05). The incidence rate of postoperative complications in study group was lower than that in control group (7.5% vs 15.38%) (P>0.05). The surgical success rate in study group was higher than that in control group (100% vs 64.1%) (P<0.05). Conclusions: YAG laser peripheral iridotomy has significant pressure-reduction effects in the treatment of refractory glaucoma, and it has high surgical success rate.