Abstract：Objective: To analyze the value of CRP combined with SAA in the differential diagnosis of bacterial pneumonia and mycoplasma pneumonia in children. Methods: :From December 2016 to December 2018, 100 cases of children hospitalized due to pulmonary infection in our hospital were selected and divided into two groups according to their infection status. Group a was a total of 75 cases of children with mycoplasma infection, while group b was a total of 25 cases of children with bacterial infection. Twenty healthy children who came to our hospital for physical examination in the same period were selected as the control group. The c-reactive protein level and serum amyloid A level of the three groups were determined and analyzed by ROC curve. Results: The CRP level and SAA level of children in the control group were significantly lower than those in group a and b, and the CRP level and SAA level of children in group a were significantly lower than those in group b (all P < 0.05). SAA/CRP ratios were not significantly different among the three groups (all P > 0.05). SAA test has a high diagnostic accuracy for children with bacterial infection and mycoplasma infection, while CRP test only has a high diagnostic accuracy for children with bacterial infection and has little significance for the differential diagnosis of children with mycoplasma infection. Conclusion: The detection of CRP and SAA has high accuracy in the diagnosis of bacterial infection in children, and the detection of SAA in the diagnosis and differential diagnosis of mycoplasma pneumoniae infection in children is also of high application value. It is worth popularizing and applying in clinic.
邓文成, 王万党, 张杰良, 杨旭然. CRP联合SAA在小儿细菌性肺炎与支原体肺炎鉴别诊断中的应用价值[J]. 河北医学, 2019, 25(10): 1737-1740.
DENG Wencheng, WANG Wandang, ZHANG Jieliang, et al. Value of CRP combined with SAA in differential diagnosis of bacterial pneumonia and Mycoplasma pneumonia in Children. HeBei Med, 2019, 25(10): 1737-1740.
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2019, Vol. 25 
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