Abstract：Objective: To investigate the effect of Sanhuang lotion on wound infection after tibiofibular fracture surgery. Methods: 108 patients with wound infection after tibiofibular fracture surgery were selected from January 2016 to March 2018 in our hospital. The patients were divided into study group and control group by random number table method, with 54 cases in each group. The control group was treated with conventional Western medicine, and the research group was treated with Sanhuang lotion on this basis. The therapeutic effect of the two groups was compared. Results: The levels of serum CRP (10.90+4.57) mg/L, IL-6 (72.76+11.96) ng/L, TNF-alpha (28.66+4.42) ng/L [CRP (10.90+4.57) mg/L, IL-6 (72.76+11.96) ng/L, TNF-alpha (28.66+4.42) ng/L] in the study group were significantly lower than those in the control group (P<0.05). The number of dressing changes in the study group was significantly less than that in the control group (8.89 (+2.16). Incision closure rate was 100%, limb function score (91.55 (+5.79) was significantly higher than that in the control group. Incision healing time (12.42 (+2.77) days) and rehabilitation cycle (15.96 (+3.90) weeks) were significantly shorter than those in the control group. There was a significant difference between the two groups (P < 0.05). The pain score of the study group (4.90 +0.80) was significantly lower than that of the control group (6.37 +0.93), and the difference between the two groups was statistically significant (P < 0.05). Conclusion: Sanhuang lotion can effectively control wound infection after tibiofibular fracture surgery, reduce inflammation reaction and promote wound healing. The therapeutic effect is good, and it is worth recommending.
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2019, Vol. 25 
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