Abstract：Objectives: To study and analyze the effect of different anesthetic compatibility on cognitive function of elderly patients undergoing laparoscopic cholecystectomy. Methods: 60 elderly patients undergoing laparoscopic cholecystectomy from March 2015 to March 2017 in our hospital were selected as study objects. According to the random number method, the observation group was divided into observation group and control group, and the observation group was anesthetized with dexmetoimidine-remifentanil sevoflurane. The control group was anesthetized with midazolam-fentanyl-isoflurane. The recovery time of spontaneous respiration, the recovery of directional force, the time of eye opening and the time of tracheal extubation were compared between the two groups. MMSE through the Mini-Psychiatric scale cognitive function was evaluated and compared before and after anesthesia. Results: The observation group and the control group received MAP in different time after anesthesia, no significant differences in HR and BIS (P>0.05). The observation group orientation recovery time and recovery time of spontaneous breathing was significantly shorter than the control group. There was significant difference between the groups (t=4.977,3.377, P<0.05). The observation group patients in the postoperative 2h and MMSE were 12h total scores were (24.95 + 1.49)% and (26.95 + 2.49)%, significantly higher than those of control group (20.6 + 1.6)% and (22.45+1.45), group The difference was statistically significant (P<0.005). Conclusion: The clinical effect of dexmedetomidine-remifentanil-sevoflurane combined anesthesia in elderly patients undergoing laparoscopic cholecystectomy is obvious, and the cognitive function recovers well after operation.
李冠军. 两种麻醉药物配伍对老年腹腔镜患者术后认知功能的影响[J]. 河北医学, 2019, 25(1): 5-8.
LI Guanjun. Two Kinds of Anesthesia Methods on the Postoperative Cognitive Function of Elderly Patients with Laparoscopy. HeBei Med, 2019, 25(1): 5-8.
2019, Vol. 25 
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