Abstract：Objective: To analyze the effect of the pressure-controlled volume-guaranteed (PCV-VG) mode on the correlation between PaCO2 and PetCO2 during one lung ventilation. Methods: A total of 60 patients with radical resection of esophageal carcinoma were selected, aged 35-65 yr, were divided into 2 groups (n=30 each) using a random number table: volume-controlled ventilation group (group V) and PCV-VG group (group P). The ventilator settings were adjusted, with a tidal volume 8 mL/kg and respiratory rate 12 breaths/min during two-lung ventilation (TLV), and with a tidal volume 6 mL/kg and respiratory rate 15 breaths/min during OLV. The inspiratory/expiratory ratio was 1:2 and 75% fraction of inspired oxygen(FiO2) at 1.5L/min. Arterial blood gas analysis and respiration parameter were determined 15 minutes after TLV (T0), 15 min (T1), 30 min (T2), 60 min (T3), 90 min (T4) after OLV. Results: Ppeak and Pplat in group V were higher than that in group P at all time points.There was no statistical difference in PaO2 between the two groups at each time point (P=0.612), and PaO2 at t1-t4 was lower than that of the same group (P <0.001).The correlation coefficient between PaCO2 and PetCO2 in P group was higher than that in V group at each time point, but the correlation between PaCO2 and PetCO2 in the other two groups was lower than that in T0 group. Conclusion: Compared with VCV ventilation, single lung ventilation with PCV-VG model can better maintain the correlation between PaCO2 and PetCO2. Compared with double lung ventilation, the correlation between PaCO2 and PetCO2 in the two ventilation modes are both decreased. In addition, the PCV-VG model can effectively reduce the peak airway pressure and airway plateau pressure and reduce the risk of lung pressure injury while ensuring oxygen supply. It can be safely used in one-lung ventilation after radical resection of esophageal cancer.
王坤, 王莉萍, 胡杰, 孙艳斌, 张承民. PCV-VG模式对单肺通气患者术中PaCO2与PetCO2相关性影响的研究[J]. 河北医学, 2019, 25(1): 167-170.
WANG Kun, WANG Liping, et al. Effect of PCV-VG Mode on Correlation between PaCO2 and PetCO2 During One-lung Ventilation. HeBei Med, 2019, 25(1): 167-170.
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2019, Vol. 25 
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