Abstract：Objective: To compare the clinical efficacy of transurethral resection of bladder tumor and selective green laser in the treatment of bladder urothelial carcinoma. Methods: 78 patients with non invasive invasive bladder urothelial carcinoma (NMIBC) treated in our hospital were selected as the study subjects. They were divided into two groups according to the different treatment methods,electro cutting group and laser group, 39 cases in each group,transurethral resection of bladder tumor was performed in the transurethral resection group,the patients in the laser group were treated with selective green laser.The intraoperative, postoperative and adverse reactions were compared between the two groups; No recurrence, overall survival, and overall survival were analyzed within 3 years using Kaplan-Meier retention analysis. Results: The operation time, blood transfusion rate, obturator nerve reflex and perforation in the operation group were higher than those in the laser group, but the difference was not statistically significant (P>0.05). The amount of bleeding in the laser group and the amount of irrigation after operation were lower than those in the cut group, indwelling time of catheter and the length of hospital stay were shorter than those of electric cutting group, the difference was statistically significant (P<0.05).The incidence of adverse reactions in the electric cutting group (35.89%) was higher than that in the laser group (28.21%),the main adverse reactions include frequent urination, urgency, dysuria, hematuria, nausea, vomiting, fever, there was no significant difference between different types (P>0.05).The survival rate in the 3 year group (89.74%) was lower than that in the laser group (94.87%), the recurrence rate (25.64%) was higher than that of laser group (10.26%), the difference was not statistically significant (P>0.05).The average recurrence time of the electric cutting group was higher than that of the laser group, the difference was statistically significant (P<0.05).There was no significant difference between the two groups in the relapse free survival curve and the overall survival curve(χ2=0.629,P=0.428;χ2=0.58,P=0.445). Conclusion: Selective green laser treatment of bladder urothelial carcinoma is less traumatic, less bleeding, less clinical adverse reaction and low recurrence rate. The effect is better than traditional urethral resection of urinary bladder tumor. It is an effective method for the treatment of bladder urothelial carcinoma.
李勇, 徐志刚, 程文广. 尿道膀胱肿瘤电切术与绿激光治疗膀胱尿路上皮癌的疗效对比[J]. 河北医学, 2018, 24(9): 1544-1547.
LI Yong, XU Zhigang, et al. Comparison of Transurethral Resection of Bladder Tumor and Green Laser in the treatment of Bladder Urothelial Carcinoma. HeBei Med, 2018, 24(9): 1544-1547.
2018, Vol. 24 
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