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河北医学  2018, Vol. 24 Issue (9): 1515-1518    DOI: 10.3969/j.issn.1006-6233.2018.09.029
  临床研究 本期目录 | 过刊浏览 | 高级检索 |
溃疡性结肠炎内镜下活动度和病理特点的关系
张海涛, 孙浩, 李凯, 许发功
青海省中医院, 青海 西宁 810000
Correlation between the Endoscopic Grade of Active UC and Pathological Characteristics
ZHANG Haitao, SUN Hao, LI Kai, et al
Qinghai Traditional Chinese Medicine Hospital, Qinghai Xining 810000, China
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摘要 目的: 探讨溃疡性结肠炎内镜下活动度与病理特点的关系。 方法: 回顾性分析2014年5月至2017年5月130例UC患者临床资料,应用Olympus CF-H260AI电子肠镜进行检查。 结果: 活动期UC的电子肠内镜下活动分级:Ⅰ级患者30例、Ⅱ级患者50例、Ⅲ级患者24例,Ⅳ级患者26例。病变范围:直肠11例、直肠乙状结肠35例、左半结肠10例、右半结肠11例、区域型3例、全结肠15例、左侧远端结直肠45例。Ⅰ级、Ⅱ级、Ⅲ级、Ⅳ级内镜活动患者均有弥漫性及非弥漫性炎症,不同内镜下活动分级弥漫性炎症与非弥漫性炎症所占的比例具有显著差异(P<0.05),且内镜下活动各级弥漫性炎症构成比高于非弥漫性炎症构成比。Ⅳ级内镜活动患者糜烂/溃疡形成、隐窝紊乱、隐窝炎、隐窝脓肿、潘氏细胞生化发生率高于Ⅰ级、Ⅱ级、Ⅲ级内镜下活动分级,比较无统计学意义(P>0.05)。内镜下活动分级与杯状细胞减少、腺体异常增生发生率比较有差异(P<0.05),其中Ⅳ级内镜活动患者的杯状细胞减少发生淋巴及轻中度腺体异常增生发生率显著高于其他Ⅰ级、Ⅱ级、Ⅲ级内镜下活动分级(P<0.05)。内镜下活动分级与AI、ESR、血便次数、血便程度、白蛋白有关(P<0.05),与Hb无关(P>0.05)。 结论: 活动期UC的内镜特点:活动度以Ⅳ级和Ⅱ级为主,病变范围以左侧远端结肠直肠为主。内镜活动度与病理特点有关,且与AI、ESR、粘液血便的程度及次数有一定的关联性。
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张海涛
孙浩
李凯
许发功
关键词 溃疡性结肠炎 内 镜 活动度 病 理    
AbstractObjective: To investigate the correlation between the endoscopic endoscopic grade of active UC and pathological characteristics. Methods: The clinical data of 130 UC patients admitted to our hospital in May 2014 to 2017 in May were retrospectively analyzed. Lympus CF-H260I electronic colonoscopy was used for examination. Results: Activity grading of active UC under electronic enteroscopy: 30 patients with grade I, 50 patients with grade II, 24 patients with grade III, 26 patients with grade IV. Scope of lesion: rectum 11 cases, rectosigmoid 35 cases, left colon 10 cases, right colon 11 cases, regional 3 cases, total colon 15 cases, left distal colorectal 45 cases. The proportion of diffuse inflammation and non-diffuse inflammation in different endoscopic activity classes was significantly different (P<0.05), and the proportion of diffuse inflammation in different endoscopic activity classes was higher than that in non-diffuse inflammation. Inflammation of different grade endoscopic activity of ulcerative colitis were significantly different(P<0.05). The incidence of endoscopic activity of ulcerative colitics /Ulcerative, the crypt disorder, cryptitis, recess abscess in grade Ⅳ were higher than other grade , and had no statistical significance.(P>0.05). There was difference in diminution of goblet cell and the incidence of abnormal hyperplasia of glands(P<0.05),and grade Ⅳ was significantly higher than other grade.(P<0.05)The endoscopic grade of active UC was related to AI,ESR,frequency of bloody stool, loody purulent stool(P<0.05),And has no relationship with Hb, albumen. Conclusion: Endoscopic features of active UC: the activity was mainly grade IV and grade II, and the lesion was mainly located in the left distal colon and rectum. Endoscopic activity was correlated with pathological features, and was correlated with AI, ESR, the degree and frequency of mucous bloody stool.
Key wordsUlcerative colitics    Enddoscopy    Mobility    Pathology
    
基金资助:青海省卫生厅医药卫生科研指导性计划,(编号:2012-wjzdx-50)
引用本文:   
张海涛, 孙浩, 李凯, 许发功. 溃疡性结肠炎内镜下活动度和病理特点的关系[J]. 河北医学, 2018, 24(9): 1515-1518.
ZHANG Haitao, SUN Hao, LI Kai, et al. Correlation between the Endoscopic Grade of Active UC and Pathological Characteristics. HeBei Med, 2018, 24(9): 1515-1518.
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http://www.hbyxzzs.cn/CN/10.3969/j.issn.1006-6233.2018.09.029     或     http://www.hbyxzzs.cn/CN/Y2018/V24/I9/1515
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