Abstract:Objective: To investigate the changes of serum liver transaminase levels in patients with closed abdominal trauma and its significance in liver injury. Methods: A total of 157 patients with closed abdominal trauma admitted to our hospital from August 2010 to August 2017 were selected as the study objects. The patients were divided into liver injury group (77 cases) and no liver injury group (80 cases) according to the presence or absence of liver injury.According to the grading standards established by the American College of Trauma Surgery (AAST), the liver injury group was divided into two groups: mild liver injury group (I-II grade, 32 cases), moderate grade group (III grade, 22 cases) Grade, 23 cases). According to the treatment, they were divided into operation group (32 cases) and conservative group (45 cases).The expression levels of alanine aminotransferase (alt), aspartate transaminase (AST) and γ -glutamyltransferase (GGT) were observed and compared. Results: the levels of ALT, AST and GGT in liver injury group were (274.15±33.19) U/L, (283.65±35.42) U/L, (46.24±6.07) U/L, which was higher than that in the group without liver injury (35.06±4.72) U/L, (58.96±7.21) U/L, (25.62±7.21) U/L, the difference was statistically significant (t= 63.773,55.562,25.595, P<0.05).The levels of ALT, AST and GGT in severe group were higher than those in mild group and mild group (P <0.05). The levels of ALT, AST and GGT in moderate group were higher than those in mild group (P <0.05).The levels of ALT, AST and GGT in the surgical treatment group were higher than those in the conservative treatment group, but the difference was not statistically significant (P> 0.05). Conclusion: The elevated level of serum liver transaminase in patients with closed abdominal trauma has high diagnostic value for liver injury and may indicate the severity of liver injury.
丁刚. 闭合性腹部外伤患者血清肝转氨酶水平变化及其与肝损伤的相关性分析[J]. 河北医学, 2018, 24(7): 1132-1134.
DING Gang. Changes of Serum Transaminase Level in Patients with Blunt Abdominal Trauma and their Correlation with Liver Injury. HeBei Med, 2018, 24(7): 1132-1134.
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