Abstract：Objective: To study the application of neuroendoscopy on hypertensive intracerebral hemorrhage and its effects on serum ferritin (SF), myelin basic protein (MBP) and glial fibrillary acidic protein (GFAP). Methods: 78 patients with hypertensive intracerebral hemorrhage admitted to our hospital from August 2014 to July 2015 were randomly divided into observation group and control group, 39 cases in each group. The observation group completed the treatment with neuroendoscopy, and the control group were taken the big bone flap craniotomy to complete the treatment. The clinical curative effect, intraoperative and postoperative situation, serum SF, MBP and GFAP levels were compared between the two groups. Results: After treatment, the total effective rate in the observation group was significantly higher than that in the control group (P<0.05). The skin incision length, cortical incision length, bone window size, operation time and blood loss in observation group were significantly less than those in control group (P<0.05). There was no significant difference in hematoma clearance rate, rebleeding rate, intracranial infection rate and mortality between the two groups (P>0.05). Before operation, there was no significant difference in serum SF, MBP and GFAP between the two groups (P>0.05). After operation, serum SF, MBP and GFAP levels in both groups were significantly lower than those before operation (P<0.05) , observation group were lower than the control group (P<0.05). Conclusion: Neuroendoscopy in the treatment of hypertensive intracerebral hemorrhage, can effectively reduce the serum levels of SF, MBP, GFAP, shorten the skin incision length, cortical incision length, operation time, reduce blood loss, clinical efficacy is good, is conducive to the prognosis of patients.
朱彬, 陈伟, 徐凤科, 虞猛, 张洪志, 道日娜, 包金锁. 神经内窥镜在高血压脑出血治疗中的应用及对血清SF MBP GFAP的影响[J]. 河北医学, 2018, 24(7): 1060-1063.
ZHU Bin, CHEN Wei, XU Fengke, et al. Application of Neuroendoscopy in the Treatment of Hypertensive Intracerebral Hemorrhage and its Effects on Serum SF MBP and GFAP. HeBei Med, 2018, 24(7): 1060-1063.
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2018, Vol. 24 
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