Abstract：Objective: To analyze the sub-clinical hypothyroidism (SCH) on pregnancy and pregnancy outcomes. Methods: 93 pregnant women (untreated group) and 42 pregnant women (treatment group) with SCH treated by L-T4 replacement therapy were enrolled in this study from October 2016 to October 2017 in our hospital. At the same time, Select the same period in our hospital for examination of 131 cases of thyroid function in pregnant women as the research object, comparative analysis of three groups of patients with pregnancy outcome. Results: (1) Compared with untreated group, the incidence of premature delivery, preeclampsia, fetal growth restriction, placental abruption, gestational hypertension and neonatal body weight were significantly lower in the treatment group than in the untreated group. There was a statistical difference (P<0.05); (2) In the untreated group and the control group, the incidences of premature delivery, preeclampsia, fetal growth restriction, and placental abruption were significantly lower in the control group than in the untreated group. Differences (P<0.05); (3) There was no statistical difference in incidence of preterm labor, preeclampsia, pregnancy-induced hypertension, placental abruption, neonatal weight loss, and fetal growth restriction between the treatment group and the control group. (P>0.05). Conclusion: SCH will lead to adverse pregnancy outcomes pregnant women, as soon as possible to give effective treatment can effectively improve pregnant women's pregnancy outcomes, reduce the incidence of complications.
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2018, Vol. 24 
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