Abstract：Objective:To analyze the effects of laparoscopic pelvic nerve-sparing radical hysterectomy combined with pelvic lymphadenectomy in the treatment of cervical cancer and the effect on vesicorectal function. Methods:The clinical data of 140 patients with cervical cancer treated in our hospital from February 2014 to January 2016 were collected. According to the treatment of pelvic nerve during operation, the patients were divided into the retention group (treated by laparoscopic pelvic nerve-sparing radical hysterectomy and pelvic lymphadenectomy, n=64) and non-retention group (treated by radical hysterectomy and pelvic lymphadenectomy, n=76).The operation, postoperative recovery and recovery of vesicorectal function were compared between the two groups. Urodynamic test was performed in the two groups before operation and 3 months after operation. The bladder compliance, the maximum urine flow rate, maximum bladder capacity and maximum detrusor systolic pressure were measured. The incidence of postoperative complications was statistically analyzed. All patients were followed up for 1 year, and the improvement of quality of life (QOL) was evaluated by the Functional Assessment of Cancer Therapy-Cervix (FACT-Cx). Results:①There were no significant differences between the two groups in operation time, intraoperative blood loss, number of dissected lymph nodes, the length of parametrial resection and the length of vaginal resection (P>0.05). ②The postoperative anal exhaust time, indwelling catheter time and hospital stay of the retention group were shorter than those of the non-retention group (P<0.05). ③The incidence rates of urinary symptoms and complications were significantly lower in the retention group than in the non-retention group(P<0.05).④After operation, the bladder compliance, the maximum urine flow rate and maximum detrusor systolic pressure were decreased while the maximum bladder capacity was increased in the two groups (P<0.05). After operation, the bladder compliance, the maximum urine flow rate and maximum detrusor systolic pressure in the retention group were higher than those in the non-retention group (P<0.05), and the scores of quality of life were higher than those in the non-retention group (P<0.05). Conclusion:The application of laparoscopic pelvic nerve-sparing radical hysterectomy combined with pelvic lymphadenectomy in the treatment of cervical cancer can protect the vesicorectal function in patients and improve the quality of life of patients.
2018, Vol. 24 
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