Abstract：Objetive: To explore the risk factors and clinical significance of refractory Mycoplasma pneumoniae pneumonia (RMPP). Methods: The clinical data of 109 children with Mycoplasma pneumoniae were retrospectively analyzed. The clinical data of 49 cases of refractory Mycoplasma pneumoniae pneumonia and 60 cases of Mycoplasma pneumoniae pneumonia (MPP) were compared, and Logsitic regression analysis was performed. Results: RMPP had a long >10 day with a long duration of heat and high incidence of extrapulmonary complications. The imaging changed in a large area of one side of the lung, involving two lobes above the lobes, and pleural effusion, especially in the right upper lung. CRP (C reactive protein) and LDH (lactate dehydrogenase) were significantly higher in the laboratory. Logsitic regression analysis showed that the independent risk factor for RMPP was long heat course, multiple pleural effusion, right upper lung disease, CRP and LDH increased significantly (P <0.05). Conclusions: Thermal process is more than 10 days, mainly seen on the top of the right lung, CRP>40mg/L, LDH>410U/L. It raises a clinical significance of distinguish early period of RMPP.
2018, Vol. 24 
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