纳米碳在cN0甲状腺乳头状癌VI区淋巴结清扫及甲状旁腺保护中的应用

doi:10.3969/j.issn.1006-6233.2018.04.026

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摘要 目的:研究纳米碳在cN0甲状腺乳头状癌VI区淋巴结清扫及甲状旁腺保护中的应用。方法:选取2016年7月至2017年7月79例cN0甲状腺乳头状癌患者,随机分为纳米碳组(41例),对照组(38例),比较两组患者一般情况,对比分析两组患者术后平均获取淋巴结总数、直径>1.0cm、0.5~1.0cm及<0.5cm淋巴结数目、转移淋巴结数目、淋巴结转移患者比率、病理甲状旁腺检出率、术后第一日PTH和血Ca、手术时间、术后引流量。结果:纳米碳组与对照组一般情况比较均无差异。纳米碳组与对照组相比,平均获取淋巴结个数、0.5~1.0cm及<0.5cm淋巴结数目更多,淋巴结转移患者比率更高,而直径>1.0cm淋巴结数目无明显差异,纳米碳组术后暂时性低PTH及甲状旁腺误损减少。手术时间及术后引流量无差别。结论:纳米碳可以增加cN0甲状腺乳头状癌VI区淋巴结清扫数目及阳性淋巴结数目,尤其是直径较小的淋巴结,可提高淋巴结转移患者检出率,减少甲状旁腺损伤,降低术后暂时性低PTH率。

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	张传灼
	李江利

关键词 ：纳米碳, 甲状腺乳头状癌, 甲状旁腺, 中央区淋巴结清扫

Abstract：Objective: To study the application of carbon nanoparticle in VI region lymph nodes dissection and parathyroid gland protection for patients with cN0 papillary thyroid carcinoma. Methods: 79 cases of cN0 thyroid papillary carcinoma admitted to Department of general surgery in Jiangsu Province Traditional Chinese Medicine Hospital from July 2016 to July 2017 were randomly divided into nano carbon group (41 cases) and control group (38 cases). The general situation of the two groups was compared. Comparative analysis of two groups of patients after obtaining the average total number of lymph nodes, the diameter of >1.0cm, 0.5~1.0cm and <0.5cm lymph node number and the number of metastatic lymph nodes and lymph node metastasis rate, detection rate, pathological parathyroid first day after the operation, PTH and blood Ca, operation time, postoperative drainage. Results: There was no significant difference in the general condition between the carbon nanoparticle trace group and the control group. Comparative analysis of two groups of patients after obtaining the average total number of lymph nodes, the diameter of >1.0cm, 0.5~1.0cm and <0.5cm lymph node number and the number of metastatic lymph nodes and lymph node metastasis rate, detection rate, pathological parathyroid first day after the operation, PTH and blood Ca, operation time, postoperative drainage. There was no difference between the operation time and the postoperative flow rate. Conclusion: Nano carbon can increase the number of lymph node dissection and the number of positive lymph nodes in VI area of cN0 thyroid papillary carcinoma, especially the smaller diameter lymph nodes. It can improve the detection rate of lymph node metastasis, reduce parathyroid damage and reduce the temporary low PTH rate after operation.

Key words： Carbon nanoparticle Papillary thyroid carcinoma Parathyroid gland Central lymph node dissection

通讯作者: 李江利

引用本文:

张传灼, 李江利. 纳米碳在cN0甲状腺乳头状癌VI区淋巴结清扫及甲状旁腺保护中的应用[J]. 河北医学, 2018, 24(4): 627-629.
ZHANG Chuanzhuo, LI Jiangli. The Application of Carbon Nanoparticle in VI Region Lymph Nodes Dissection and Parathyroid Gland Protection for Patients with cN0 Papillary Thyroid Carcinoma. HeBei Med, 2018, 24(4): 627-629.

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http://www.hbyxzzs.cn/CN/10.3969/j.issn.1006-6233.2018.04.026 或 http://www.hbyxzzs.cn/CN/Y2018/V24/I4/627

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