Abstract：Objective: To investigate the clinical effect of azithromycin in the treatment of Mycoplasma pneumoniae infection in children with upper respiratory tract. Methods: 100 cases of upper respiratory tract mycoplasma pneumoniae infection in our hospital from October 2016 to July 2017 were randomly divided into two groups, azithromycin group receiving azithromycin and clarithromycin group receiving clarithromycin, The clinical indicators, the overall treatment effect, the related disease parameters and the adverse reactions of the two groups were compared. Results: The antipyretic time, the disappearance of cough, the disappearance of rales and the disappearance of wheeze in the azithromycin group were significantly lower than those in the clarithromycin group; the cure rate was significantly higher than that in the clarithromycin group; after treatment, the lymphocytes , IgA, IgE and IgG levels were significantly higher than the clarithromycin group, CRP and IL-4 levels were significantly lower than the clarithromycin group, there was a significant difference (P <0.01); two groups of children There was no significant difference in adverse reaction rate of all kinds of drugs (P> 0.05). Conclusion: azithromycin in children with upper respiratory tract infection Mycoplasma pneumoniae clinical effect is significant, higher safety, with reference.
蔡亲武, 杨子江, 王昌乐. 阿奇霉素治疗小儿上呼吸道肺炎支原体感染临床效果观察[J]. 河北医学, 2018, 24(2): 328-332.
CAI Qinwu, YANG Zijiang, WANG Changle. Clinical Observation of Azithromycin in treating Mycoplasma Pneumoniae Infection in Children with Upper Respiratory Tract. HeBei Med, 2018, 24(2): 328-332.
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2018, Vol. 24 
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