Abstract:Objective: To compare the application of two different ways of vascular recanalization (mechanical thrombectomy and arterial thrombolysis) in acute cerebral artery occlusion. Methods: The clinical data of 68 patients with mechanical thrombectomy in our hospital and 50 cases of arterial thrombolytic patients were retrospectively analyzed. The changes of NIHSS score before and after operation, puncture to repassage time, blood vessel repassage rate, incidence of intracranial hemorrhage, mortality and 3 months mRs after operation were compared between the two groups. Results: The time of the puncture and repassage of the patients in the mechanical thrombectomy group was significantly lower than that of the arterial thrombolytic group (P<0.05); the repassage rate of the patients in the mechanical thrombectomy group was significantly higher than that of the arterial thrombolysis group (P<0.05). The total incidence rate of intracranial hemorrhage were significantly lower than that in the arterial thrombolytic group (P<0.05); and there was no significant difference between the two groups after 3 months' mRS score and the NIHSS score (P>0.05); the good prognosis rate of the patients in the mechanical thrombectomy group was significantly better than that in the arterial thrombolysis group (P<0.05) at 3 months. Conclusion: Compared with the thrombolytic therapy, the treatment of thrombolytic therapy for the patients with acute cerebral artery occlusion has a wider time window, with a higher repassage rate, lower bleeding rate, which is beneficial to improve the prognosis of the patients, and should be advocated in clinical.
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