Abstract：Objective: To investigate the effect of propofol anesthesia maintenance on patients' anesthesia effect and postoperative cognitive function during total hysterectomy. Methods: 87 patients were treated with total hysterectomy from January 2017 to January 2018 in our hospital. According to the different methods of anesthesia, the patients were divided into the observation group (n=45) and the control group (n=42). The control group was given seven halothane during the operation, while the observation group was given propofol anesthesia during the operation. The changes of blood glucose, cortisol, heart rate, arterial pressure and cognitive function were observed before and after treatment in the two groups. The time of spontaneous breathing recovery, opening time, extubation time, setting time of force recovery were recorded, and the incidence of adverse reaction after treatment was compared. Results: After treatment, the levels of cortisol, blood sugar and other stress responses in the two groups were higher than those before treatment, but the above indexes in the observation group were significantly lower than those in the control group(P<0.05). After treatment, the heart rate and arterial pressure in the two groups were lower than those before the treatment, and the above indexes were significantly higher than those in the control group (P<0.05). After treatment, the cognitive work of the two groups of patients was found. They all decreased, but the observation group was higher than that of the control group (P<0.05). After treatment, the time of spontaneous breathing recovery, opening time, extubation time and restoring time were shorter in the observation group than in the control group (P<0.05). During the treatment, the two groups had adverse reactions such as extubation and choking, restlessness, malignant vomiting, waking delay and shivering. The total incidence of the observation group was 11.11%. 33.33% (P<0.05) was lower than that of the control group. Conclusion: The intervention of propofol anesthesia in patients with total hysterectomy can reduce the stress response and inflammatory reaction of the body. It has little effect on the cognitive function of the patients, the effect of anesthesia is good, the adverse reaction is small, and the effect is remarkable. It is worthy of clinical application.
邓韦韦. 术中丙泊酚麻醉维持对全子宫切除术患者麻醉苏醒期及术后认知功能的影响[J]. 河北医学, 2018, 24(10): 1647-1650.
DENG Weiwei. Effect of Propofol Anesthesia during Anesthesia on Recovery Period and Postoperative Cognitive Function in Patients Undergoing Total Hysterectomy. HeBei Med, 2018, 24(10): 1647-1650.
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2018, Vol. 24 
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