Abstract：Objective: To observe the changes of renin, angiotensin II (ATII) and aldosterone (ALD) in plasma of patients with acute myocardial infarction (AMI) at different sites of infarction. Methods: A total of 49 patients with anterior wall AMI, 39 patients with inferior wall AMI, 29 patients with acute non-ST segment elevation myocardial infarction (NSTEMI) and 20 patients with unstable angina pectoris (UA) were enrolled in this study. (BNP), left ventricular end-diastolic diameter (LV), ejection fraction (EF) and so on were recorded and compared between the two groups. Results: Renin 16.73 (8.42, 33.12) in the anterior wall AMI group, Renin 18.98 (8.30,30.41) in the inferior wall AMI group and Renin 15.27 (P = 0.009) in the NSTEMI group were significantly higher than those in the UA group (P <0.05). There was no significant difference between the two groups (P> 0.05). There was no significant difference in the level of Renin between the two groups (P> 0.05). Renin and ATII were correlated with Rs = 0.157 (P <0.05). ALD was correlated with ATII (Rs = 0.325, P <0.01). Conclusion: The level of Renin in the early stage of AMI was higher than that in the control group. There was no significant difference in the Renin level between the two groups. There was no significant difference in ATII and ALD between the two groups, but there was correlation between Renin, ATII and ALD.
李舒承, 王虹, 刘超, 张爱文. 不同部位心肌梗死急性期肾素血管紧张素醛固酮变化分析[J]. 河北医学, 2018, 24(1): 90-95.
LI Shucheng, WANG Hong, LIU Chao, et al. Changes of Rennin Angiotensin Aldosterone in Acute Myocardial Infarction in Different Parts. HeBei Med, 2018, 24(1): 90-95.
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2018, Vol. 24 
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