Analysis of Clinical Risk Factors of Placental Abruption during Pregnancy
LIU Jiuying, CAI Xiaonan, CAO Ming
Wuhan Children's Hospital, Wuhan Maternal and Child Healthcare Hospital, Tongji Medical College, Huazhong University of Science & Technology, Hubei Wuhan 430016, China
Abstract:Objective: To investigate the clinical risk factors of PA in 167 cases of placental abruption (PA). Methods: Clinical data of 167 cases with placental abruption were retrospectively reviewed in Wuhan Children's Hospital from Jan.2007 to Dec. 2012. The data of PA pregnant women's age, residence, parity, twin or multiple pregnancy, prenatal vaginal bleeding, rupture of membranes, blood pressure, time of activity, there is no trauma, umbilical cord, oxytocin, chronic cough and constipation during pregnancy, placental abruption type were analyzed retrospectively. Results: The incidence of placental abruption was 0.56% including emergency patients accounting for 82.04%.105 cases had the main predisposing factors(62.87% ), mainly including hypertensive disorders of pregnancy, premature rupture of fetal membranes, with oxytocin and traumatic factors. Conclusion: Pay more attention to prenatal care, pregnant women with high risk factors of PA, once the occurrence of PA, as soon as possible diagnosis, active treatment, improve maternal outcome.
刘久英, 蔡晓楠, 曹铭. 孕期发生胎盘早剥的临床危险因素分析[J]. 河北医学, 2017, 23(5): 764-766.
LIU Jiuying, CAI Xiaonan, CAO Ming. Analysis of Clinical Risk Factors of Placental Abruption during Pregnancy. 河北医学, 2017, 23(5): 764-766.
[1] TikkanenM.Placentalabruption:epidemiology,risk factors and consequen[J].Acta ObstetGynecol Scand,2011,90 ( 2):140. [2] 谢幸,苟文丽.妇产科学[M].第8版.北京:人民卫生出版社,2014.129~132. [3] Matsubara S,Usui R,Ohkuchi A. Misquoting Page's classification for placental abruption in Japan [J].ObstetGynaecol Res,2011,37 ( 5) : 481. [4] 华克勤,丰有吉.实用妇产科学[M].第3版:北京:人民卫生出版社,2013.155~157. [5] 赵祖英,陆洁清.15例胎盘早剥临床分析[J].齐齐哈尔医学院学报,2012,33(10):1318~1319. [6] 钱红燕.不典型胎盘早剥56例临床分析[J].中国妇幼保健杂志,2010,25(4):475~476. [7] 何玉华,桂定清.胎盘早剥的高危因素及临床分析[J].四川医学,2011,32(2):178~180. [8] 上海市胎盘早剥调查协作组.上海市胎盘早期剥离10年发病情况的研究[J].上海医学,2003,26(10):699~701. [9] 程国梅,张曦,崔世红.胎膜早破并发胎盘早剥的临床分析[J].中国妇产科临床杂志,2004,6(3):169~171. [10] 陈卫民.孕妇外伤后胎盘早剥16例临床资料分析[J].苏州大学学报(医学版)2006,26(3):502~507. [11] 虞晴,张霞.静脉滴注右旋糖苷40过敏致重型胎盘早剥1例[J].中国实用妇科与产科杂志,2014,30(11):909~910. [12] 汤洪,殷朝晖,孟雅静.嗜铬细胞瘤引起胎盘早剥一例[J].临床误诊误治,2006,19(9):15. [13] 陈云书,张翠荣.腹泻致胎盘早剥1例[J].Chinese General Practice,2004,7(22):1678. [14] 张喜红.重度子痫前期并发胎盘早剥的临床分析[J].中国妇幼保健2012;27(5):669~670. [15] Kharfi A,Giguere Y,Sapin V,et al. Trophoblastic remodeling innormal and preeclamptic pregnancies: implication of cytokines[J].ClinBiochem,2003,36( 5):323~331. [16] 彭婷,李笑天.妊娠期高血压疾病并发胎盘功能障碍性疾病及其诊治[J].中国实用妇科与产科杂志2011:27(12):902~905. [17] Wang YN,Yang Z. Multivariate analysis of risk factors with placental abruption in preeclampsia[J].Zhonghua Fu Chan KeZaZhi,2010,45( 11) : 825~828. [18] 卢国荣.重度子痫前期患者生化指标与胎盘早剥的关系研究[J].中国妇幼保健2012;27(18):2740~2742. [19] 刘宝瑛,钟梅,刘国柄.胎盘早剥的病因及诊治分析[J].中国优生与遗传杂志,2003,11:97~98. [20] 严兆华,李英勇.胎盘早剥63例临床分析[J].广东医学院学报,1999,17:256~257. [21] Kim YM, Chaiworapongsa T, Gomez R, et al. Failure of physio-logic transformation of the spiral arteries in the placental bed inpreterm premature rupture of membranes[J].Am Obstet Gynecol,2002, 187: 1127~ 1142. [22] Major CA, Veciana M, Lewis M, et al. Preterm premature rupture of membranes and abruptio placenta: Is there an association between these pregnancy complications[J]. Am ObstetGynecol, 1995,172: 672~ 676. [23] 许建娟许倩.血清CA125用于胎盘早剥早期诊断的探讨[J].苏州大学学报(医学版)2002;22(3):321~322. [24] 李景平,王欢华,吴利玲.血栓调节素及CA125联合超声检查对胎盘早剥的早期诊断价值[J].新乡医学院学报,2012,29(1);40~44. [25] García-CavazosR,Colín-Valenzuela A,Espinoy Sosa S. Alpha-fetoprotein as an early predictor of adverse perinatal outcome[J].GinecolObstet Mex,2010,78(5):268. [26] 罗远材.血清D-二聚体测定对诊断胎盘早剥的应用价值[J].现代妇产科进展:2006;15(1):70~71.