Analysis of the Effect of Shugan Mingmu Decoction combined with Mecobalamin on Liver qi Stagnation in patients with Primary Intraocular pressure, Glaucoma Visual Acuity and CRP
CAI Xiaojun, ZHAO Xiaolong
Heilongjiang University of Chinese Medicine, Heilongjiang Harbin 150001, China
Abstract：Objective: To study the impact analysis of Shugan Mingmu decoction combined with Mecobalamin on patients with liver qi stagnation primary open-angle glaucoma intraocular pressure,visual acuity and CRP. Methods: 156 cases (274 eyes) of patients with stagnation of liver Qi POAG. admitted in our hospital from January 2015 to December 2016 were selected as objects. The patients were divided into observation group 78 cases (136 eyes) and control group 78 cases (138 eyes) according to the digital method. The two patients were treated with mecobalamin. The patients in the observation group were treated with Shugan Mingmu Decoction combined mecobalamin. The IOP, visual acuity, CRP level and adverse reactions were compared between the two groups before and after treatment for 3 months. Results: The cure rate of the observation group was 57.69%,the total effective rate was 94.87%, compared with the control group of 30.77% and 84.62% were significantly higher, the difference was statistically significant(P<0.05). After treatment, the IOP reduced value and visual acuity rise value of the observation group were significantly higher than those of the control group, the difference was statistically significant(P<0.05).After treatment,the levels of CRP in the observation group was significantly lower than control group,the difference was statistically significant(P<0.05).There was no significant difference in the total incidence of allergies, anorexia, nausea, vomiting and diarrhea, as well as adverse events in the observation group (P > 0.05). Conclusion: Using Shugan Mingmu Decoction and Mecobalamin in treatment of liver qi stagnation POAG patients with better curative effect, also can effectively improve the intraocular pressure,visual acuity and the level of CRP, which is worthy of promotion
蔡萧君, 赵晓龙. 疏肝明目汤联合甲钴胺对肝郁气滞型原发性开角型青光眼患者眼压视敏度及CRP的影响分析[J]. 河北医学, 2017, 23(4): 675-678.
CAI Xiaojun, ZHAO Xiaolong. Analysis of the Effect of Shugan Mingmu Decoction combined with Mecobalamin on Liver qi Stagnation in patients with Primary Intraocular pressure, Glaucoma Visual Acuity and CRP. 河北医学, 2017, 23(4): 675-678.
[1] 马臻舜.明目汤联合甲钴胺治疗青光眼视神经损害疗效观察[J].上海中医药杂志,2013,47(5):72~73. [2] 陈慧,李小敏,刘韶瑞,等.晚期青光眼视神经功能的保护及效果研究[J].中华全科医学,2012,10(7):1034~1036. [3] 陈涛,马娜.补精益视片联合甲钴胺片治疗眼压控制后青光眼疗效观察[J].陕西中医,2015,36(10):1385~1386. [4] 王玉元.晚期青光眼术后联合药物治疗的效果观察[J].临床合理用药杂志,2012,5(1):71~72. [5] 邬明军,马小兵.祛火明目合剂联合甲钴胺对青光眼术后视神经功能的影响[J].中国乡村医药,2016,23(21):38~39. [6] Pahlitzsch M,Gonnermann J,Maier AB,et al.Modified goniotomy as an alternative to trabectome in primary open angle glaucoma and pseudoexfoliation glaucoma:1 year results[J].Can OphthalmoL,2017,52(1):92~98. [7] 郭继援.疏肝明目汤联合西药治疗肝郁气滞型原发性开角型青光眼临床观察[J].四川中医,2015,33(7):97~98. [8] Wagdy FM.Canaloplasty versus viscocanalostomy in primary open angle glaucoma[J].Electron Physician,2017,9(1):3665~3671. [9] 张静,李翔.补肾活血中药治疗原发性闭角型青光眼的临床观察[J].湖北中医杂志,2014,36(3):10~11. [10] 杨芳,刘爽,杨艳蓓,等.疏肝明目汤联合甲钴胺对126例肝郁气滞型原发性开角型青光眼患者眼压及视敏度的影响分析[J].中外女性健康研究,2016,3(18):188~189. [11] 贾洪亮,万琦,胡粒山,等.疏肝明目饮联合复明片对青光眼术后视野疗效观察[J].现代诊断与治疗,2014,25(14):3164~3166. [12] Jiang MM,Zhou Q,Liu XY,et al.Structural and functional brain changes in early-and mid-stage primary open-angle glaucoma using voxel-based morphometry and functional magnetic resonance imaging[J].Medicine(Baltimore),2017,96(9):6139~6140. [13] 祁颖,郝燕燕.甲钴胺对青光眼视神经保护作用的临床研究[J].中华临床医师杂志(电子版),2013,7(3):1298~1300.
2017, Vol. 23 
冀公网安备13080202000677号