Abstract：Objective: To investigate the antimicrobial resistance of Helicobacter pylori eradication in Chengde area and to explore the related treatment protocols. Method: Gastric mucosa specimens of 1036 cases of patents with Hp infection by endoscopy from March 2014 to December 2016 in Chengde Central Hospital, were cultured for Hp, 448 strains of clinic isolates were obtained, 9 kinds of antibacterial drug susceptibility test were taken to analyze drug resistance. Result: The sensitivity of amoxiciuim, amoxiciuim/clavulanute potassium and clarithromycin for the Chengde area's Hp was high, therefore the drug resistance rate was lower. Conclusion: Amoxicilln, amoxicilln/clarithromycin and clarithromycin can continue to be the top choice for the eradication of Hp in Chengde area. Tetracycline, furazolidone, levoifloxacin and moxifioxacin can be used as second-line drugs and the remedial treatment or treatment protocols again.
2017, Vol. 23 
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