Abstract：Objective: To investigate the correlation of the levels of uric acid with inflammation factor in type 2 diabetes. Methods: One hundred and seven cases of patients with type 2 diabetes were divided into contral group, microalbuminuria group and clinical proteinuria group according to urinary albumin to creatinine ratio, the levels of uric acid and C-reactive protein were detected. Results: The levels of uric acid and C-reactive protein,TNF-α,ICAM-1 of contral group, microalbuminuria group and clinical proteinuria group were on the rise, the differences were statistically significant(P<0.05), the levels of uric acid with C-reactive protein,TNF-α,ICAM-1 were positively correlated. Conclusion: Uric acid leading to diabetic nephropathy through inflammatory reaction in type 2 diabetes.
何建秋, 张蕊, 孙志新, 王英南, 王丽红, 刘畅, 韩桂艳. 2型糖尿病肾病患者血尿酸与炎症因子的相关性研究[J]. 河北医学, 2017, 23(3): 430-432.
HE Jianqiu, ZHANG Rui, SUN Zhixin, et al. Correlation Study of the Levels of Uric Acid With Inflammation Factor in Type 2 Diabetes. HeBei Med, 2017, 23(3): 430-432.
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2017, Vol. 23 
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