Abstract：Objective: To analyze serum thyroid hormone level change of chronic obstructive pulmonary disease and the correlation between the severity of disease. Methods: 41 cases of patients with chronic obstructive pulmonary disease in remission and 123 cases in exacerbation (including PaO2>60mmHg, 40mmHg<PaO2<60mmHg and PaO2<40mmHg group) from April 2013 to September 2015 in our hospital and 41 cases of healthy people by routine check-up in our hospital during the same period were selected, then the serum thyroid hormone levels were determined. Results: Compared with healthy control group, TT3, FT3, TT4, FT4, TSH level in remission group has no statistical difference(P > 0.05), while compared with the rest of the two groups, all indexes in exacerbation group were significantly lower (P < 0.05).And TT3, FT3, TT4, FT4, TSH levels in moderate hypoxia group significantly decreased compared with those in relatively mild hypoxia (P < 0.05). The level of each index in severe hypoxia group significantly decreased compared with the moderate hypoxia group (P < 0.05). There was statistical difference in detection index level between three groups. Conclusion: The serum thyroid hormone level of chronic obstructive pulmonary disease is positively correlated with disease severity, level changes are more apparent as the pathological changes, clinical detection is of great significance in lesion severity judgment.
2017, Vol. 23 
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