Abstract:Objective: To analyze the elderly head and neck cancer underwent CT treatment plans for two-way influence the dose distribution of radiation, in order to provide reference for the clinical. Methods: From March 2015 to March 2016, the elderly patients with head and neck cancer radiotherapy, were diagnosed by pathology for head and neck cancer, IMRT, a total of 12 patients were collected: 8 cases of nasopharyngeal carcinoma, 2 cases of tonsil carcinoma, 1 case of laryngeal carcinoma, 1 case of tongue cancer, among them 11 cases of male patients and 1 female patient, a comparison process and after radiotherapy of the following indicators: target and organ at risk, parotid gland volume, parotid mass and body midline distance. Results: A two-way process and after radiotherapy, the left and right sides of the parotid gland volume were reduced after treatment (P<0.05), left and right sides of parotid mass and body midline distance were reduced (P<0.05); GTV/PTV D2, Cheng D50, D95, D98, D100 is less than a ride, D95, D98, GTV in the second D100, PTV D50, D95, D98, D100, HI, CI is a low (P<0.05); two-way in bilateral parotid V26, mean dose and right parotid gland V26, the average dose was increased (P <0.05). Conclusion: The elderly head and neck cancer CT plan two-way radiation dose, V26, bilateral parotid mean dose of PTV and GTV, D95, D98 and D100 and PTV doses were significantly different. Clinical attention should be paid to the anatomical structure of patients with large differences, should be at the right time to modify the treatment plan to enhance the treatment effect of patients.
汪谢嫒, 张贵海, 冯光勇, 张莹莹, 吴明娜, 帅颐. 中老年头颈部肿瘤行二程CT再计划对放射治疗剂量分布影响的临床研究[J]. 河北医学, 2017, 23(2): 177-179.
WANG Xieyuan, ZHANG Guihai, FENG Guangyong, et al. Clinical Study of Elderly Head and Neck Cancer line CT Plan Dose Distribution in Two-way Influence on Radiation. HeBei Med, 2017, 23(2): 177-179.
[1] Arduíno DM,Raquel Esteves A,Cortes L,et al.Mitochondrial metabolism in parkinson's disease impairs quality control autophagy by hampering microtubule-dependent traffic[J].Human Molecular Genetics,2012,21(21):4680~4702. [2] 曹焱,张超.血清癌胚抗原和细胞角蛋白19片段对食管癌患者放疗效果及生存状况的评估[J].中国肿瘤临床与康复,2015,22(11):1284~1287. [3] 115th annual meeting of the american associaton of colleges of pharmacy[J].American Journal of Pharmaceutical Education,2014,78(5):111. [4] 张文博,齐曼,王立志,等.中晚期宫颈癌外照射阶段三维适形放疗和共面等分设野调强放疗计划探讨[J].河北医学,2016,22(11):1818~1821. [5] Korsholm ME,Waring LW,Edmund JM.A criterion for the reliable use of MRI-only radiotherapy[J].Radiation Oncology(London,England),2014,9:16. [6] 董可,黄拔群,刘跃龙,等.头颈部肿瘤调强放疗计划的剂量验证研究[J].中国现代医学杂志,2014,24(12):43~46. [7] Orefice LL,Waterhouse EG,Partridge JG,et al.Distinct roles for somatically and dendritically synthesized brain-derived neurotrophic factor in morphogenesis of dendritic spines[J].The Journal of Neuroscience,2013,33(28):11618~11632. [8] 白文文,周志国,宋玉芝,等.颈段食管癌三维适形与调强放疗的剂量学及临床对比研究[J].中华放射医学与防护杂志,2014,34(12):919~921. [9] Konigsberg B,Hess R,Hartman C,et al.Inter-and intraobserver reliability of two-dimensional CT scan for total knee arthroplasty component malrotation[J].Clinical Orthopaedics and Related Research,2014,472(1):212~217. [10] 李雪南,修霞,李高峰,等.比较两种CT模拟定位方法在调强放疗中的误差影响[J].中华放射肿瘤学杂志,2013,22(5):387~390.