加味秦艽鳖甲汤治疗2型糖尿病合并初治涂阳肺结核的临床疗效

doi:10.3969/j.issn.1006-6233.2017.12.048

摘要
图/表
参考文献
相关文章 (15)

全文: PDF (1389 KB) HTML (1 KB)
输出: BibTeX | EndNote (RIS)

摘要 目的:观察加味秦艽鳖甲汤治疗2型糖尿病合并初治涂阳肺结核的临床疗效。方法:选取2型糖尿病合并初治涂阳肺结核患者300例,将其随机分为两组,对照组采用常规降糖、抗结核药物治疗,治疗组在对照组的基础上采用加味秦艽鳖甲汤口服并雾化吸入治疗,治疗6个月后评价临床疗效。结果:两组治疗6个月末FBG、2hPBG、HbA1c水平及咳嗽、咳痰、喘息、肺部啰音评分均低于治疗前,差异具有统计学意义(P<0.05),治疗组降低程度大于对照组,差异具有统计学意义(P<0.05);治疗组治疗6个月末痰菌转阴率、空洞闭合率、病灶有效吸收率及治愈率高于对照组,差异具有统计学意义(P<0.05)。结论:在常规降糖及抗结核治疗的基础上联合加味秦艽鳖甲汤治疗2型糖尿病合并初治涂阳肺结核,能够更好的控制血糖,促进痰菌转阴、病灶吸收及空洞闭合,改善咳嗽、咳痰、喘息、肺部啰音等临床症状,提高临床疗效。

	服务

	把本文推荐给朋友
	加入我的书架
	加入引用管理器
	E-mail Alert
	RSS
	作者相关文章

关键词 ：加味秦艽鳖甲汤, 2型糖尿病, 初治涂阳肺结核, 临床疗效

Abstract：Objective: To observe the clinical efficacy of jiawei qinjiao biejia decoction in the treatment of type 2 diabetes mellitus combined with newly diagnosed smear-positive pulmonary tuberculosis. Methods: 300 patients with type 2 diabetes mellitus complicated with newly diagnosed smear-positive pulmonary tuberculosis were randomly divided into two groups. The control group was treated with conventional hypoglycemic and anti-tuberculosis drugs. The treatment group was treated on the basis of the control group jiawei qinjiao biejia decoction and aerosol inhalation treatment, 6 months after treatment to evaluate the clinical efficacy. Results: The levels of FBG, 2hPBG, HbA1c and cough, sputum, wheezing and pulmonary rales in the two groups were lower than those in the control group, the difference was statistically significant (P<0.05), and the treatment group was lower than the control group, the difference was statistically significant (P<0.05). The effective rate of wound healing, cure rate and cure rate were higher in the treatment group than in the control group, the difference was statistically significant (P<0.05). Conclusion: The combination of jiawei qinjiao biejia decoction in the treatment of type 2 diabetes mellitus combined with newly diagnosed smear-positive pulmonary tuberculosis can better control blood sugar, promote sputum negative, lesion absorption and empty closure, and improve cough, sputum, wheezing, lung rales and other clinical symptoms, improve clinical efficacy.

Key words： Jiawei qinjiao biejia decoction Type 2 diabetes mellitus Newly diagnosed smear positive pulmonary tuberculosis Clinical efficacy

基金资助:河北省中医药管理局科研计划项目,(编号:2015064)

通讯作者: 田彦卿

引用本文:

王岫峥,张皓,刁丽丽,王栋,李蕊,赵磊,田彦卿. 加味秦艽鳖甲汤治疗2型糖尿病合并初治涂阳肺结核的临床疗效[J]. 河北医学, 2017, 23(12): 2092-2095.
WANG Xiuzheng, ZHANG Hao, DIAO Lili, et al. Clinical Efficacy on Treatment of Type 2 Diabetes Mellitus Combined with Primary Treatment of Pulmonary Tuberculosis with Jiawei qinjiao biejia Decoction. HeBei Med, 2017, 23(12): 2092-2095.

链接本文:

http://www.hbyxzzs.cn/CN/10.3969/j.issn.1006-6233.2017.12.048 或 http://www.hbyxzzs.cn/CN/Y2017/V23/I12/2092

[1] 杨贵发.2型糖尿病合并肺结核患者治疗方案的选择与评估[J].临床肺科杂志,2012,17(7):1269~1270.
[2] Baker MA,Harries AD,Jeon CY,et al. The impact of diabetes on tuberculosis treatment outcomes: a systematic review[J].BMC Med,2011,9(81):1~15.
[3] 中华医学会结核病学分会.肺结核诊断和治疗指南[J].中华结核和呼吸杂志,2001,24(2):70~74.
[4] 中华医学会糖尿病学分会.中国2型糖尿病防治指南(2013年版)[J].中国糖尿病杂志,2014,22(8):2~42.
[5] 中华人民共和国卫生部.肺结核门诊诊疗规范(2012年版)[J].中国医学前沿杂志(电子版),2013,5(3):73~75.
[6] 武剑,舒薇,李世元,等.肺结核合并糖尿病流行现状及其危险因素研究进展[J].疾病监测与控制杂志,2015,9(2):93~94.
[7] 毛晓辉,王勃,曹思哲.糖尿病合并肺结核的流行病学及诊治现状[J].临床肺科杂志,2016,21(12):2300~2302.
[8] 聂安正,林志健,王雨,等.秦艽化学成分及药理作用研究进展[J].中草药,2017,48(3):597~608.
[9] 杨丹,都艳玲,赵楠,等.青蒿素及其衍生物的药理作用研究进展[J].吉林医药学院学报,2014,35(2):132~134.
[10] 李彬,郭力城.鳖甲的化学成分和药理作用研究概况[J].中医药信息,2009,26(1):25~27.
[11] 李红伟,孟祥乐.地黄化学成分和药理作用研究进展[J].药物评价研究,2015,38(2):218~228.
[12] 冯菲.知母的药理作用研究进展[J].中医临床研究,2017,9(12):133,137.
[13] 胡云飞,徐国兵.牡丹皮及其主要成分丹皮酚的药理作用研究进展[J].安徽医药,2014,18(4):589~592.
[14] 郑海群.地骨皮降血糖药理作用的研究进展[J].中国处方药,2016,14(3):13~14.
[15] 孙晓卉,张量.柴胡药理作用的研究进展[J].中国医药导报,2017,14(10):52~55.
[16] 张小琼,侯晓军,杨敏,等.乌梅的药理作用研究[J].中国药房,2016,27(25):3567~3570.