Analysis of the Effect of Early Application of Xingnaojing Injection on Patients with Long-term Rehabilitation Efficacy and Safety of Cerebral Hemorrhage
WANG Liying, ZHU Haixia
The Affiliated Hospital of Inner Mongolia Medical University, Inner Mongolia Hohhot 010050, China
Abstract:Objective: To study the effect of early application of Xingnaojing Injection on patients with long-term rehabilitation efficacy and safety of cerebral hemorrhage. Methods: 94 cases of cerebral hemorrhage patients admitted in our hospital from July 2014 to September 2015 were selected. According to the random number table method, all the patients were divided into observation group and control group, each had 47 cases. The control group were given routine treatment, the observation group was treated with Xingnaojing injection treatment on the basis of the control group. The clinical efficacy, activities of daily living, neurological function and complications were compared between the two groups after treatment. Results: The total effective rate of the observation group was 93.62% (44/47), which was significantly higher than 78.72% of the control group (37/47), the difference was statistically significant (P < 0.05). After treatment, the number of barrier free activities of daily living in the observation group was significantly higher than that in the control group, while the number of severe functional impairment was significantly lower than that of the control group, the differences were statistically significant (P < 0.05). After treatment, the neurological deficit scores of the two groups were significantly lower than before treatment, while the observation group was significantly lower than that of the control group, the differences were statistically significant (P < 0.05). There were no significant differences in the incidence of pneumonia, renal function damage and cerebral edema between the two groups, and the difference was not statistically significant (P > 0.05). Conclusion: Early application of Xingnaojing Injection in treatment of cerebral hemorrhage has significant clinical efficacy, and can improve the activities of daily living of patients and the nerve function, good safety.
王丽英, 朱海霞. 早期应用醒脑静注射液对脑出血患者远期康复疗效及安全性的影响分析[J]. 河北医学, 2017, 23(11): 1892-1894.
WANG Liying, ZHU Haixia. Analysis of the Effect of Early Application of Xingnaojing Injection on Patients with Long-term Rehabilitation Efficacy and Safety of Cerebral Hemorrhage. HeBei Med, 2017, 23(11): 1892-1894.
[1] Yoshida J, Kubo Y, Yoshida K,et al.Development of intracerebral hemorrhageand subarachnoid hemorrhage shortly after cerebralInfarction onset in an adult patient with moyamoya disease[J].No Shinkei Geka,2017,45(2):139~146. [2] Malinova V, Psychogios MN, Tsogkas I,et al.MR-angiography allows defining severity grades ofcerebralvasospasm in an experimental double blood injection subarachnoidhemorrhagemodel in rats[J].PLoS One,2017,12(2):171121~171122. [3] 程鹏玲,于春丽,宋闰宇,等.依达拉奉联合醒脑静治疗急性脑出血的临床疗效观察[J].现代生物医学进展,2016,16(4):751~754. [4] 李学,王增光.头颅局部亚低温联合醒脑静治疗急性脑出血疗效观察[J].淮海医药,2017,35(1):5~7. [5] 刘雅英.依达拉奉联合醒脑静对急性脑出血的临床疗效[J].中国医药指南,2016,14(24):88. [6] Leys D.The management of acutecerebralischaemia is now just a matter of organization. For spontaneous intracerebralhemorrhage, all has still to be done[J].Presse Med,2017,46(1):1~3. [7] Mahale RR, Mehta A, Shankar AK,et al.Bilateral cerebral hemorrhagein herpes simplex encephalitis: rare occurrence[J].Neurosci Rural Pract,2016,7(1):128~130. [8] 章雯秀.醒脑静注射液治疗急性脑出血的临床疗效观察[J].中西医结合心脑血管病杂志,2016,14(20):2442~2445. [9] 王佩军,潘艳艳.醒脑静治疗脑出血急性期患者的疗效和安全性分析[J].西南国防医药,2016,26(2):187~189. [10] 潘家兴,吴勇,陈旭,等.醒脑静注射液联合纳洛酮对急性脑出血伴意识障碍患者神经功能的影响[J].现代中西医结合杂志,2016,25(25):2829~2831. [11] 方程.醒脑静注射液治疗脑出血并发症的疗效观察[J].中西医结合心血管病电子杂志,2016,4(15):161.