Abstract：Objective: To investigate the effect of laparoscopic resection of pancreatic body and tail on splenic immune function and blood supply in spleen. Methods: The clinical data of 80 cases underwent splenectomy and pancreatic body resection were retrospectively analyzed. The changes of immune function and the blood supply of spleen after open pancreatectomy and laparoscopic resection of pancreatic body and tail were compared. Results: The levels of IgG and CD4+ and CD8+T cells in the two groups were lower than those before operation (P<0.05). The level of IgG in the observation group after 1 days was higher than that in the control group, and the scores of CD4+ and CD8+T cells were lower than those of the control group (P<0.05). Two groups of patients had postoperative arteriovenous patency decreased (P<0.05); In the postoperative, the observation group patients arteriovenous patency was significantly higher than the control group (P<0.05). After 1 month, the spleen perfusion in the observation group was significantly better than that in the control group (P<0.05). Conclusion: The short-term prognosis of laparoscopic pancreatic body and tail resection is better than that of laparotomy group, and has less influence on the immune function.
丁兵, 蒋辉. 腹腔镜行胰体尾切除术患者术后对脾脏中免疫功能及脾脏血液供应的影响[J]. 河北医学, 2017, 23(10): 1615-1618.
DING Bing, JIANG Hui. Effect of Laparoscopic Resection of Pancreatic Body and Tail on |Splenic Immune Function and Blood Supply in Spleen. 河北医学, 2017, 23(10): 1615-1618.
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2017, Vol. 23 
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