Abstract:Objective: To observe the changes of serum thyroid stimulating hormone (TSH) level, carotid intima-media thickness (IMT) and pulse wave velocity (PWV) in elderly patients with H-type hypertension, and to analyze the association among them. Methods: A total of 145 elderly patients with H-type hypertension, admitted to our hospital from April 2021 to May 2024, were included. Carotid IMT, PWV, and TSH levels were measured, and the correlation between TSH levels, IMT, and PWV was analyzed. Results: The IMT and PWV levels in patients with abnormal TSH were higher than those in patients with normal TSH, with significant differences (P < 0.05). The TSH and PWV levels in patients with abnormal IMT were higher than those in patients with normal IMT, with significant differences (P < 0.05). The TSH and IMT levels in patients with abnormal PWV were higher than those in patients with normal PWV, with significant differences (P < 0.05). Multiple linear regression analysis showed that disease duration, body mass index (BMI), and TSH were influencing factors for IMT in patients with H-type hypertension (P < 0.05). Disease duration, BMI, TSH, and IMT were influencing factors for PWV in patients with H-type hypertension (P < 0.05). Conclusion: Abnormal serum TSH levels in elderly patients with H-type hypertension are associated with increased carotid IMT and PWV, which may be related to the development of carotid atherosclerosis.
熊凌杰, 梁立龙, 李远远, 陈劲. 老年H型高血压患者血清TSH颈动脉内膜厚度及PWV的相关性研究[J]. 河北医学, 2025, 31(2): 326-330.
XIONG Lingjie, LIANG Lilong, LI Yuanyuan, et al. Study on the Correlation Between Serum TSH Carotid Intima-Media Thickness, and PWV in Elderly Patients with H-type Hypertension. HeBei Med, 2025, 31(2): 326-330.
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