Study on the Therapeutic Efficacy and Serum Tumor Markers Levels of Patients with Ultrasound-guided Interventional Therapy for Ovarian Endometrioid Cyst
ZHANG Rui, REN Yongfeng, XU Yanlan, et al
Bozhou People's Hospital, Anhui Bozhou 236000, China
Abstract：Objective: To investigate the efficacy and serum tumor markers levels of patients with ultrasound-guided interventional therapy for ovarian endometrioid cyst. Methods: A total of 80 patients with ovarian endometrioid cyst admitted to our hospital from May 2019 to May 2022 were randomly divided into two groups: 40 cases in the control group underwent laparoscopic cystectomy, and 40 cases in the study group underwent ultrasound-guided interventional therapy. The clinical efficacy, operation time, antibiotic use time, and hospital stay were compared between the two groups. The serum tumor marker levels and ovarian function indexes were evaluated before and after the operation. The recurrence rate of the two groups was observed one year after operation. Results: The clinical efficacy of the study group was higher than that of the control group (P<0.05). The operation time, antibiotic usage time, and hospitalization time of the study group were shorter than those of the control group (P<0.05). 6 months after the operation, the serum Carbohydra Antigen 125 (CA125),Carbohydra Antigen 199 (CA199) and Human epididymal protein 4 (HE4) levels in the study group were lower than those in the control group (P<0.05). Six months after the operation, estrogen (E2) level in the study group was lower than that in the control group, Follicle Stimulating Hormones (FSH) and Luteinizing Hormones (LH) levels in the study group were higher than those in the control group (P<0.05). The recurrence rate in the study group was lower than that in the control group 1 year after operation (P<0.05). Conclusion: The use of ultrasound-guided invasive puncture in the treatment of patients with adenometrioid cysts of the ovaries can enhance the efficacy and reduce the level of serum tumor markers, improve the function of the ovaries, and reduce the rate of postoperative relapse.
2024, Vol. 30 
冀公网安备13080202000677号