Abstract：Objective: To explore the occurrence of metabolic syndrome (MS) and its relationship with ovulation induction outcomes in infertility patients with polycystic ovary syndrome (PCOS). Methods: A total of 225 infertile PCOS patients admitted from January 2020 to April 2023 were selected as the study subjects, and the occurrence of MS was recorded. Based on whether MS occurred or not, patients were divided into the MS group and the non-MS group. Clinical data were compared between the two groups, and the relationship between MS and ovulation induction outcomes was analyzed. Results: Among the 225 PCOS infertile patients, 31 patients had concomitant MS, accounting for 13.78%. In the MS group, BMI (≥24 kg/m2), waist circumference (≥88cm), systolic blood pressure (≥130 mmHg), diastolic blood pressure (≥85 mmHg), FPG (≥126 mg/dL), TG (≥150 mg/dL), FINS, HOMA-IR levels were higher than those in the non-MS group, while HDL-C (≥59 mg/dL) level was lower than the non-MS group (P<0.05). The ovulation rate and clinical pregnancy rate in the MS group were lower than those in the non-MS group (χ2=6.745; χ2=5.292, P<0.05). Binary logistic analysis showed that age (≥30 years), waist circumference (≥88cm), MS (yes), FINS, HOMA-IR, estradiol (E2), testosterone (T), anti-Müllerian hormone (AMH) were independent risk factors affecting ovulation induction outcomes in PCOS infertile patients (P<0.05). Conclusion: The occurrence of MS is relatively high in PCOS infertile patients, and it is correlated with ovulation induction outcomes. Ovulation induction outcomes are influenced by factors such as age, waist circumference, MS, FINS, HOMA-IR, E2, T, AMH.
邹璇, 李进, 蒋韬. PCOS不孕合并代谢综合征发生情况及其与促排卵结局的关系分析[J]. 河北医学, 2024, 30(1): 135-141.
ZOU Xuan, LI Jin, JIANG Tao. Occurrence of Metabolic Syndrome in Infertile Patients with Polycystic Ovary Syndrome (PCOS) and Its Relationship with Ovulation Induction Outcomes. HeBei Med, 2024, 30(1): 135-141.
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2024, Vol. 30 
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