Clinical Study on the Combination of Yaotongning Capsule and Spinal Micro-Adjustment Manipulation on Improving Pain and Lumbar Dysfunction in Patients with Discogenic Low Back Pain
YAN Fei, CHEN Xingyan, FAN Haijing, et al
The Affiliated Hospital of Chengde Medical College, Hebei Chengde 067000, China
Abstract：Objective: To study the clinical efficacy and safety of spinal micro-adjustment manipulation combined with drug Yaotongning capsule in treating discogenic low back pain (DLBP) with cold-dampness obstruction syndrome. Methods: Seventy patients with DLBP were randomly divided into a treatment group and control group,35 cases in each group. Yaotongning capsules and spinal micro-adjustment manipulation were used to treat the patients in the treatment group, whereas Diclofenac sodium sustained-release tablets and spinal micro-adjustment manipulation were used to treat the patients in the control group.The Oswestry disability index (ODI), Japanese orthopaedic association scores (JOA), visual analogue scale (VAS) and safety indicators of the two groups were compared and evaluated before treatment and 1,3 and 6 weeks after treatment. The satisfaction rate with the evaluation of lumbar function improvement is 97%, the improvement rate of lumbar function is 86%, and the overall excellent and good rate is 97%.. Results: After 1 week,3 weeks and 6 weeks of treatment, patients in the two groups had improvements in their VAS, ODI, and JOA scores when compared to their pre-treatment scores (P<0.05). The treatment group's effectiveness was inferior to the control group's before three post-operative weeks, but it was comparable to that of the control group by six weeks. However, the treatment group experienced fewer adverse responses than the control group did at that time. Conclusion: Spinal micro-adjustment manipulation combined with Chinese patent medicine Yaotongning capsule could significantly improve the clinical symptom of DLBP with cold-dampness obstruction syndrome, and the effect was more obvious after 6 weeks of treatment.
晏飞, 陈星燃, 范海静, 侯莹莹, 谢双喜, 李连泰, 付世杰. 腰痛宁胶囊联合整脊手法对改善椎间盘源性腰痛患者疼痛及腰部功能障碍的临床研究[J]. 河北医学, 2023, 29(8): 1362-1367.
YAN Fei, CHEN Xingyan, FAN Haijing, et al. Clinical Study on the Combination of Yaotongning Capsule and Spinal Micro-Adjustment Manipulation on Improving Pain and Lumbar Dysfunction in Patients with Discogenic Low Back Pain. HeBei Med, 2023, 29(8): 1362-1367.
[1] Quinones S,Konschake M,Aguilar LL,et al.Clinical anatomy of the lumbar sinuvertebral nerve with regard to discogenic low back pain and review of literature[J].Eur Spine,2021,30(10):2999-3008. [2] Park WM,McCall IW,O' Brien JP,et al.Fissuring of the posterior annulus fibrosus in the lumbar spine[J].Br Radiol,1979,52(617):381-387. [3] 彭卫珍,陈华,孔令春.双氯芬酸钠致不良反应46例分析[J].医药导报,2012,31(3):392-394. [4] 谢煜,朱杰彬.试述《黄帝内经》对腰痛的认识[J].中医学报,2017,32(12):2390-2392. [5] 周楠,房敏,朱清广,等.脊柱微调手法治疗腰椎间盘突出症的腰背肌生物力学性能评价[J].中国康复医学杂志,2012,27(2):115-119. [6] 王志文.腰椎骨性关节炎患者的福音[J].家庭中医药,2016,6(6):55. [7] 孙庆,钟成梁,张玮,等.腰痛宁胶囊治疗腰椎骨性关节炎寒湿瘀阻证240例多中心随机对照临床研究[J].中医杂志,2019,60(3):224-228. [8] 胥少汀,葛宝丰,徐印坎.实用骨科学[M].第4版.北京:人民军医出版社,2015.2086-2095. [9] 国家中医药管理局.中医病证诊断疗效标准[M].南京:南京大学出版社,1994.201-203. [10] 郭斌.不同麻醉方式及术中护理联合参芪颗粒对74例骨科手术患者血流动力学及血浆TNF-α和IL-6水平的影响分析[J].东方药膳,2019,(20):184. [11] Shirado O,Doi T,Akai M,et al.An outcome measure for Japanese people with chronic low back pain:an introduction and validation study of Japan low back pain evaluation questionnaire[J].Spine (Phila Pa 1976),2007,32(26):3052-3059. [12] 晏飞,陈星燃,侯莹莹,等.三痹汤加减联合脊柱微调整脊手法治疗椎间盘源性腰痛急性期的临床观察[J].中国中医急症,2022,31(11):1997-2000. [13] 晏飞,陈星燃,侯莹莹,等.腰痛宁胶囊联合双氯芬酸钠缓释片治疗椎间盘源性腰痛的临床观察[J].中草药,2022,53(4):1112-1116.
2023, Vol. 29 
冀公网安备13080202000677号