Abstract：Objective: To explore the effect of Q self-traction method in the treatment of early esophageal cancer and its influence on the incidence rates of complications. Methods: Retrospective analysis was performed on the clinical data of 184 patients with early esophageal cancer admitted to the hospital from June 2019 to June 2022. According to different surgical methods, the patients were divided into observation group (89 cases, Q self-traction method) and control group (95 cases, standard endoscopic submucosal dissection). Perioperative indicators, therapeutic effect, occurrence of complications, and recurrence and scores of Generic Quality of Life Inventory-74 (GQOLI-74) at 6 months after surgery were compared between the two groups. Results: The intra-operative blood loss, dissection time, surgical time and hospital stay in observation group were shorter than those in control group (P<0.05). There were no statistically significant differences in the en bloc resection rate and curative resection rate between the two groups (P>0.05). There were no statistical differences in the incidence rates of various complications between the two groups (P>0.05), but the total incidence rate of complications in observation group was lower than that in control group (P<0.05). At 6 months of follow-up after surgery, there was 1 case of recurrence (1.12%) in observation group and 3 cases of recurrence (3.16%) in control group (P>0.05). The scores of items of GQOLI-74 showed no statistical differences between the two groups before surgery (P>0.05), and the GQOLI-74 scores at 6 months after surgery were significantly increased (P<0.05), and the increase of scores in observation group were higher compared with those in control group (P<0.05). Conclusion: Q self-traction method can optimize ESD operation for early esophageal cancer, and its therapeutic effect is comparable to that of traditional ESD, but the incidence rates of complications are low and the quality of life of patients is significantly improved.
王青, 刘雷, 谢鹏飞. Q法自牵引技术治疗早期食管癌的效果及对并发症发生率的影响[J]. 河北医学, 2023, 29(8): 1348-1353.
WANG Qing, LIU Lei, XIE Pengfei. Effect of Q Self-Traction Method on Early Esophageal Cancer and Its Influence on the Complication Rate. HeBei Med, 2023, 29(8): 1348-1353.
[1] Bolger JC,Donohoe CL,Lowery M,et al.Advances in the curative management of oesophageal cancer[J].Br Cancer,2022,126(5):706-717. [2] Zeng H,Ran X,An L,et al.Disparities in stage at diagnosis for five common cancers in China:a multicentre,hospital-based,observational study[J].Lancet Public Health,2021,6(12):877-887. [3] 曹耀丹,秦佳敏,文黎明.内镜黏膜下剥离术治疗大面积早期食管癌的疗效分析[J].中国内镜杂志,2023,29(3):67-72. [4] Pimentel-Nunes P,Libanio D,Bastiaansen BAJ,et al.Endoscopic submucosal dissection for superficial gastrointestinal lesions:european society of gastrointestinal endoscopy (ESGE) guideline-update 2022[J].Endoscopy,2022,54(6):591-622. [5] 陈志龙,林晓露,邓万银,等.Q法自牵引技术在大范围早期食管癌内镜黏膜下剥离术中的应用研究(含视频)[J].中华消化内镜杂志,2020,37(3):163-168. [6] Hu W,Yu J,Yao N,et al.Efficacy and safety of four different endoscopic treatments for early esophageal cancer:a network meta-analysis[J].Gastrointest Surg,2022,26(5):1097-1108. [7] Nagata M,Namiki M,Fujikawa T,et al.Impact of traction direction in traction-assisted gastric endoscopic submucosal dissection (with videos)[J].Dig Dis Sci,2023,68(6):2531-2544. [8] 姚成云,谢娟,伍平,等.不同ESD手术操作方案治疗早期食管癌效果及对围术期指标复发风险的影响与安全性分析[J].河北医学,2022,28(12):1990-1996. [9] Yu X,Liu Y,Xue L,et al.Risk factors for complications after endoscopic treatment in Chinese patients with early esophageal cancer and precancerous lesions[J].Surg Endosc,2021,35(5):2144-2153. [10] 巫雪茹,焦若男,赵思,等.食管早癌及癌前病变ESD与ESTD安全性及有效性Meta分析[J].中华肿瘤防治杂志,2020,27(6):480-489. [11] Yu M,Tan Y,Liu D.Strategies to prevent stricture after esophageal endoscopic submucosal dissection[J].Ann Transl Med,2019,7(12):271. [12] Liu Y,Qian D,Tang B,et al.Feasibility of endoscopic submucosal dissection for early esophageal squamous cell carcinoma with relative indications[J].Dig Surg,2021,38(1):14-23.
2023, Vol. 29 
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