Value of Concentrated Growth Factors Combined with Biooss Bone Substitute Materials for the Treatment of Bone Loss in Mandibular Posterior Region with Immediate Implantation
ZHANG Hongbo, SUN Chuanfeng, ZHANG Yang
Lu'an People's Hospital, Anhui Lu'an 237005, China
Abstract：Objective: To study the application value of concentrated growth factor (CGF) and Biooss bone substitute materials in mandibular implants. Methods: A total of 101 patients with immediate implant bone loss in mandibular posterior area in our hospital from June 2019 to June 2022 were retrospectively selected, and the patients were grouped according to differences in treatment regimen: 51 in observation group and 50 in control group, The control group was treated with the Biooss bone substitute material, the observation group was given concentrated growth factors on the basis of the control group.The patients were followed up by telephone and outpatient clinic 6 months after the treatment to compare the horizontal and vertical bone grafting, bone thickness and bone regeneration effects between the two groups; the clinical efficacy of the patients was evaluated according to the changes in the postoperative stability coefficients (ISQ), and the levels of bone thickness, bone density, and bone width were compared between the two groups at the immediate postoperative stage, at 3 months after the surgery and at 6 months after the surgery; and the patients were compared with respect to the degree of recovery of the postoperative masticatory function, the height of gingival papilla attachment and overall dental esthetic degree index measurements. The measured values of the patients' postoperative masticatory function recovery, gingival papilla attachment height, and overall dental esthetics were compared. At the end of the follow-up period, patients' satisfaction with the treatment was collected and the differences between groups were compared. Results: The effect of bone regeneration in the horizontal and vertical directions (94.00%,92.00%) was better than that of the control group (90.19%,86.27%). The ISQ mean of patients in control group decreased first and then increased, with the lowest ISQ score of the patients, and the ISQ mean of observation group showed an increasing trend. The ISQ mean was different between both groups at 1 week and 4 weeks after the operation, and the mean of observation group was higher than that of control group (P<0.05), but the difference between the immediate postoperative and 8 weeks was not significant (P>0.05). The immediate bone thickness, bone width and bone density values in the two groups were comparable (P>0.05); compared 3 and 6 months after surgery, and observation group was higher than serums (P<0.05). Compared with serums, the recovery degree of masticatory function, the height of the whole gingival nipple increased, with a statistically significant difference (P<0.05). The treatment satisfaction of observers was (96.00%)was higher than that of serums (84.31%), (P<0.05). Conclusion: Concentrate growth factor (CGF) and Biooss bone replacement material can improve patient satisfaction and bone regeneration effect, maintain the stability of postoperative implant, and have good clinical application effect.
张宏波, 孙传锋, 张洋. 浓缩生长因子联合Biooss骨替代材料应用于即刻种植下颌后牙区骨缺失治疗的价值[J]. 河北医学, 2023, 29(8): 1318-1324.
ZHANG Hongbo, SUN Chuanfeng, ZHANG Yang. Value of Concentrated Growth Factors Combined with Biooss Bone Substitute Materials for the Treatment of Bone Loss in Mandibular Posterior Region with Immediate Implantation. HeBei Med, 2023, 29(8): 1318-1324.
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2023, Vol. 29 
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