Abstract：Objective: To explore the influence of individual factors on the efficacy of percutaneous balloon compression in the treatment of primary trigeminal neuralgia. Methods: The clinical data of 89 PTN patients treated with PBC from November 2018 to February 2022 were analyzed retrospectively. The pain score of Barrow Neurological Institute was used to grade facial pain. The pain recurrence (BNI pain score) was followed up and recorded at 3, 6, 9 and 12 months after surgery, and patients were divided into the cure group (BNI pain score Ⅰ to Ⅱ) and recurrence group (BNI pain score Ⅲ to Ⅴ) based on the results of the follow-up at month 12, and the gender, age, body mass index (BMI), underlying disease (hypertensive disease) were analyzed between the two groups of patients, diabetes mellitus), side, disease duration, involved branches, surgical history, preoperative BNI pain score, size of the external orifice of the foramen ovale (FO) (including longitudinal diameter, transverse diameter, longitudinal diameter ratio, and transverse diameter ratio), and other individual factors and recurrence after PBC were analyzed between the two groups. Results: During the follow-up period, 18 patients experienced pain recurrence. Univariate analysis showed that there was no significant difference in sex, age, hypertension, diabetes, side, involved branches, preoperative BNI pain score, transverse diameter and transverse diameter ratio of FO between the cure group and the relapse group (P>0.05); BMI, disease duration, operation history, length to diameter and length to diameter ratio of FO were related to the postoperative effect (P<0.05). Multivariate logistic regression analysis of significant individual factors showed that BMI≥24kg/m2, disease duration≥5 years, and previous surgical history were independent risk factors for postoperative pain recurrence (P<0.05), and FO length was a protective factor for postoperative recurrence (P<0.05). ROC curve analysis showed that FO length had a predictive effect on pain recurrence after PBC (P<0.05), with a predictive effect of 68.9%. The calculated maximum Joden index is 0.359, the corresponding FO length diameter is 6.74mm, the sensitivity is 0.803, and the specificity is 0.556. Conclusion: PBC is an effective surgical treatment for PTN, and individual factors have an important impact on the recurrence of pain after PBC.
李传胜, 王昆鹏, 杨婕, 韩凤伟, 呼铁民, 张继伟, 刘兵, 闫丽娜, 刘文霞. 个体因素对经皮穿刺球囊压迫术治疗原发性三叉神经痛疗效的影响[J]. 河北医学, 2023, 29(7): 1142-1148.
LI Chuansheng, WANG Kunpeng, YANG Jie, et al. Influence of Individual Factors on the Efficacy of Percutaneous Balloon Compression in the Treatment of Primary Trigeminal Neuralgia. HeBei Med, 2023, 29(7): 1142-1148.
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2023, Vol. 29 
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