Abstract：Objective: To analyze the acupoints selected for acupuncture prescriptions and their dispensing patterns in the existing literature reports on acupuncture treatment of atopic dermatitis with Apriori algorithm based on Python, so as to expand the therapeutic ideas for clinical acupuncture treatment of atopic dermatitis. Methods: The contents of the relevant literature in CNKI, Wanfang data, and Wipu repositories (~ February 2021) that met the inclusion criteria of this study were extracted and entered, and the data were read using Python, and the Apriori algorithm was used to analyze the selected acupoints and the rules of combination for the treatment of atopic dermatitis. Results: In this study, 24 acupuncture prescriptions were selected for statistical analysis, involving a total of 38 acupoints, and the total frequency of acupoints applied was 170. Among them, the high frequency acupoints were Quchi, Xuehai, and Zusanli; the high frequency meridians involved were Foot Yang Sun Bladder Meridian, Foot Tai Yin Spleen Meridian, and Hand Yang Ming Large Intestine Meridian; the acupoints were mostly distributed in the extremities and back; Quchi-Tianshu-Zhongbei was the key acupoint for the treatment of atopic dermatitis; the visualization analysis of the combination of acupoints showed that the common combinations of acupoints were: Diaphragmatic Yu, Dazhui, Lung Yu, Heart Yu, Wei Zhong, Gall Bladder Yu, and San Jiao Yu. The cluster analysis of high-frequency acupoints showed that the acupoints could be divided into four effective clusters. Conclusion: The selection pattern of acupuncture points selected from the results of this study can provide reference value for clinical research on the acupuncture treatment of atopic dermatitis.
刘悦, 汤晓冬, 李伟红, 翟舒婕, 余洋. 基于Apriori算法的针灸治疗特应性皮炎选取腧穴规律研究[J]. 河北医学, 2023, 29(6): 916-921.
LIU Yue, TANG Xiaodong, LI Weihong, et al. Apriori Algorithm Based Acupuncture for the Treatment of Atopic Dermatitis: A Study on the Regularity of Acupoint Selection. HeBei Med, 2023, 29(6): 916-921.
[1] 中国特应性皮炎诊疗指南(2020版)[J].中华皮肤科杂志,2020,25(2):81-88. [2] Zhao B,Chen Y,Liao S,et al.Successfully treated recalcitrant atopic eczema with acupoint autohemotherapy:a case report and hypothesized mechanism of the therapy[J].Journal of Integrative Medicine,2022,13(4):224-226. [3] Wong L S,Yen Y T,Lee C H.The implications of pruritogens in the pathogenesis of atopic dermatitis[J].International Journal of Molecular Sciences,2021,22(13):7227. [4] 林薇,周琼艳,黄静,等.特应性皮炎与精神神经因素相互作用的研究进展[J].中国医药导报,2021,18(5):33-36. [5] 林颖,莫秀梅,李红毅,等.重症难治性特应性皮炎的中医药治疗思路探讨[J].广州中医药大学学报,2021,38(12):2807-2811. [6] 路坦,马琳.儿童特应性皮炎的发病机制及治疗研究进展[J].现代医药卫生,2021,37(21):3666-3670. [7] Mathiesen Sophie Maria,Thomsen Simon Francis.The prevalence of atopic dermatitis in adults:systematic review on population studies[J].Dermatology Online Journal,2019,25(8):325-326. [8] 李虹瑶.特应性皮炎中医药治疗研究热点及前沿趋势分析[D].广州中医药大学,2021. [9] 韩莹,周钰,袁红丽.子午流注择时皮肤针疗法治疗特应性皮炎的临床对照研究[J].新疆医科大学学报,2021,44(9):1036-1040. [10] 李鸣,陈三三,刘然,等.基于《针灸大成》的曲池穴穴位本意及临床应用探微[J].浙江中医药大学学报,2019,43(1):83-86. [11] 吴霞,谭金曲,沈福隆,等.曲池穴主治病症的古代文献研究[J].中医药临床杂志,2021,33(7):1285-1290. [12] 王红,吴霞,韩慧,等.火针联合西药治疗血虚风燥型特应性皮炎的临床疗效观察[J].基层中医药,2022,1(6):44-49. [13] 韩莹,景福权,孙飒,等.子午流注择时皮肤针疗法改善特应性皮炎患者皮肤屏障功能疗效观察[J].吉林中医药,2022,42(2):241-244. [14] 赵睿智.特应性皮炎中药治疗处方规律分析[D].天津中医药大学,2020. [15] 汤柳,李小磊,曹晓琴,等.基于网络药理学分析及实验验证探讨共轭亚油酸治疗特应性皮炎的作用机制[J].现代药物与临床,2022,37(10):2206-2214. [16] 余霞,汪瀚文,刘嘉玲,等.特应性皮炎与肠道菌群的相关性研究[J].皮肤病与性病,2021,43(4):480-481.
2023, Vol. 29 
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