氢氧化钙联合氯已定对根管消毒患者疼痛程度及消毒效果的影响分析

doi:10.3969/j.issn.1006-6233.2023.03.028

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摘要 目的: 通过对比氢氧化钙联合氯己定与单纯使用氢氧化钙对根管消毒患者的消毒效果与术后疼痛程度的影响,探讨不同药物的临床应用效果。方法: 选择2019年6月至2022年12月我院收治的102例根管消毒患者作为研究对象,使用随机数字表法简单随机分为联合组(n=51例)与常规组(n=51例),常规组单纯使用氢氧化钙进行根管消毒,联合组使用氢氧化钙联合氯己定进行根管消毒。封药后7d,比较两组患者的消毒效果、Mohdsulong疼痛分级、并发症发生率;根管预备前、后及封药后7d,比较两组患者根管中需氧菌与厌氧菌的菌落计数;比较两组患者封药时间。结果: 联合组的消毒有效率为98.04%,高于常规组的80.39%(P<0.05);根管预备前与根管预备后,两组需氧菌与厌氧菌数量比较,差异无统计学意义(P>0.05);封药后7d,联合组患者根管内需氧菌与厌氧菌数量均少于常规组(P<0.05);联合组的疼痛分级情况优于常规组(P<0.05);联合组封药时间短于常规组(P<0.05);联合组牙龈肿胀与总并发症的发生率低于常规组(P<0.05)。结论: 与单纯使用氢氧化钙相比,使用氢氧化钙联合氯己定进行根管消毒可获得更好的消毒效果,可有效抑制细菌繁殖,减少患者根管治疗的疼痛感,并且缩短根管治疗时间,具有较高的安全性。

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	于雪菲
	王娜娜
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	陈旭兵

关键词 ：氢氧化钙, 氯己定, 根管消毒, 疼痛程度, 消毒效果

Abstract：Objective: To compare the influence of calcium hydroxide combined with chlorhexidine and calcium hydroxide alone on the disinfection effect and postoperative pain degree in patients with root canal disinfection, and to explore the clinical application effects of different drugs. Methods: A total of 102 patients with root canal disinfection who were treated in the hospital from Jun. 2019 Dec. 2022 were selected as the research subjects, and were simply randomized into combined group (n=51) and conventional group (n=51) by using the random number table method. The conventional group adopted calcium hydroxide alone for root canal disinfection, while the combined group received calcium hydroxide combined with chlorhexidine for root canal disinfection. At 7 days after medicine sealing, the disinfection effect, Mohdsulong pain grading, and incidence rates of complications were compared between the two groups. The colony counts of aerobic bacteria and anaerobic bacteria in root canal before and after root canal preparation and at 7 days after medicine sealing and the sealing time of the two groups of patients were compared. Results: The effective rate of disinfection of the combined group was 98.04%, which was higher than 80.39% of the conventional group (P<0.05). There were no statistical differences in the counts of aerobic and anaerobic bacteria between the two groups before and after root canal preparation (P>0.05). At 7 days after medicine sealing, the counts of aerobic bacteria and anaerobic bacteria in the root canal of the combined group were less than those of the conventional group (P<0.05). The pain grading of the combined group was better compared with that of the conventional group (P<0.05), and the sealing time was shorter than that in the conventional group (P<0.05). The incidence rate of gingival swelling and total incidence rate of complications were lower in the combined group than those in the conventional group (P<0.05). Conclusion: Compared with calcium hydroxide alone, the application of calcium hydroxide combined with chlorhexidine for root canal disinfection can achieve better disinfection effect, and can more effectively inhibit the bacterial reproduction, relieve the pain of root canal treatment, and shorten the root canal treatment time, with higher safety.

Key words： Calcium hydroxide Chlorhexidine Root canal disinfection Pain degree Disinfection effect

基金资助:安徽省自然科学基金项目,(编号:1608085QH191)

通讯作者: 陈旭兵

引用本文:

于雪菲, 王娜娜, 王琼琼, 陈旭兵. 氢氧化钙联合氯已定对根管消毒患者疼痛程度及消毒效果的影响分析[J]. 河北医学, 2023, 29(3): 491-495.
YU Xuefei, WANG Nana, WANG Qiongqiong, et al. Analysis of the Effect of Calcium Hydroxide Combined with Chlorhexidine on the Pain Level and Disinfection Effect of Root Canal Disinfection in Patients. HeBei Med, 2023, 29(3): 491-495.

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http://www.hbyxzzs.cn/CN/10.3969/j.issn.1006-6233.2023.03.028 或 http://www.hbyxzzs.cn/CN/Y2023/V29/I3/491

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