COOK球囊与前列素制剂用于妊娠高血压孕妇足月引产的临床疗效对比

doi:10.3969/j.issn.1006-6233.2022.07.022

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摘要 目的: 探讨比较COOK球囊与前列素制剂用于妊娠高血压孕妇足月引产的临床疗效。方法: 选取2019年8月至2021年1月共80例足月妊娠高血压孕妇,依据简单随机化分组方法分为试验组和对照组。对照组40例孕妇采用前列素制剂引产,研究组40例孕妇采用COOK球囊引产,比较两组妊娠高血压孕妇的分娩状况、引产期间并发症、产后出血及新生儿结局。结果: 分娩状况:试验组使用COOK球囊治疗在阴道分娩、宫颈成熟度Bishop分、促宫颈成熟有效率、使用催产素例数及人工破膜例数明显高于对照组使用阴道给予米索前列醇,差异有统计学意义(P<0.05);引产期间并发症:两组孕妇在引产期间均未发生羊水栓塞,试验组在引产期间并发症发生率明显低于于对照组(22.50%vs47.50),差异有统计学意义(χ²=5.495,P=0.019);产后出血及新生儿结局:试验组在产后出血量上明显低于对照组,差异有统计学意义(t=6.973,P<0.05),两组新生儿Apgar评分、体质量、送入监护室例数、吸氧例数及并发症发生率,差异无统计学意义(P>0.05)。结论: COOK子宫颈扩张球囊用于妊娠高血压孕妇足月引产过程中,在缓解分娩状况、减少引产期间发生并发症及产后出血均优于阴道给予米索前列醇,值得临床推广。

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	孔雅俊
	安晓刚
	武志平

关键词 ： COOK子宫颈扩张球囊, 米索前列醇, 妊娠高血压, 孕妇, 足月, 引产

Abstract：Objective: To compare the clinical efficacy of cook balloon and prostaglandin preparation for full-term induction of labor in pregnant women with gestational hypertension. Methods: A total of 80 full-term pregnant women with hypertension from August 2019 to January 2021 were randomly divided into experimental group and control group.40 pregnant women in the control group were induced by prostaglandin and 40 pregnant women in the study group were induced by COOK balloon.The delivery status,complications during induction,postpartum hemorrhage and neonatal outcome of pregnant hypertensive pregnant women in the two groups were compared. Results: Delivery status:The number of vaginal deliveries,cervical maturity Bishop score,cervical maturation efficiency,oxytocin use and manual rupture of membranes were significantly higher in the experimental group than in the control group using misoprostol given vaginally,with a statistically significant difference (P<0.05).Complications during induced labor:No amniotic fluid embolism occurred during induction of labour in either group,and the incidence of complications during induction of labour was significantly lower in the experimental group than in the control group (22.50% vs.47.50),with a statistically significant difference (χ²=5.495,P=0.019).Postpartum hemorrhage and neonatal outcome:The amount of postpartum hemorrhage in the experimental group treated with cook balloon was significantly lower than that in the control group treated with misoprostol through vagina,the difference was statistically significant (t=6.973,P<0.05).There was no statistically significant difference between the two groups in terms of Apgar score,body mass,number of admissions to the nursing unit,number of cases on oxygen and complication rate (P>0.05). Conclusion: The COOK cervical dilatation balloon is superior to misoprostol given vaginally for the relief of labour,reduction of complications during induction of labour and postpartum haemorrhage during full-term induction of labour in pregnant women with gestational hypertension and is worthy of clinical promotion.

Key words： COOK cervical dilation balloon Misoprostol Pregnancy induced hypertension Pregnant woman Full term Induced labor

基金资助:山西省自然科学基金项目,(编号:2019011047)

引用本文:

孔雅俊, 安晓刚, 武志平. COOK球囊与前列素制剂用于妊娠高血压孕妇足月引产的临床疗效对比[J]. 河北医学, 2022, 28(7): 1162-1166.
KONG Yajun, AN Xiaogang, WU Zhiping. Clinical Efficacy of COOK Balloon versus Prostaglandin Preparation for Full-Term Induction of Labour in Pregnant Women with Gestational Hypertension. HeBei Med, 2022, 28(7): 1162-1166.

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http://www.hbyxzzs.cn/CN/10.3969/j.issn.1006-6233.2022.07.022 或 http://www.hbyxzzs.cn/CN/Y2022/V28/I7/1162

[1] 简珊,张灵慧,张雪,等.贵州铜仁地区17~39岁孕妇妊娠高血压综合征患病现状及危险因素[J].中国公共卫生,2019,35(4):388-392.
[2] Ju-Yueh,Li,Peng-Hui,et al.Pregnancy-induced hypertension is an independent risk factor for meconium aspiration syndrome:a retrospective population based cohort study - scienceDirect[J].Taiwanese journal of obstetrics & gynecology,2019,58(3):396-400.
[3] Felton M,Hundley V A,Grigsby S,et al.Effects of slow and deep breathing on reducing obstetric intervention in women with pregnancy-induced hypertension:a feasibility study protocol[J].Hypertension in Pregnancy,2021,40(1):1-7.
[4] Gunaratne M,Thorsteinsdottir B,Garovic V D.Combined oral contraceptive pill-Induced hypertension and hypertensive disorders of pregnancy:shared mechanisms and clinical similarities[J].Current Hypertension Reports,2021,23(5):1-13.
[5] 赵丹阳.COOK宫颈扩张球囊,欣普贝生在宫颈低评分足月妊娠初产妇引产术中的应用对比[J].山东医药,2019,59(18):61-63.
[6] Jie,Song,Ruihong,et al.Magnesium sulfate combined with nifedipine is effective in pregnancy-induced hypertension and reduces levels of serum β2-microglobulin and retinol binding protein 4[J].Iranian journal of public health,2019,48(12):2308-2310.
[7] Bakouei F,Delavar M A,Mashayekh-Amiri S,et al.Efficacy of n-3 fatty acids supplementation on the prevention of pregnancy induced-hypertension or preeclampsia:a systematic review and meta-analysis[J].Taiwanese Journal of Obstetrics and Gynecology,2020,59(1):8-15.
[8] Younes S T,Ryan M J.Pathophysiology of cerebral vascular dysfunction in pregnancy-induced hypertension[J].Current Hypertension Reports,2019,21(7):52-54.
[9] Snc A,Phwbcd E,Mfh A,et al.Maternal pregnancy-induced hypertension increases the subsequent risk of neonatal candidiasis:a nationwide population-based cohort study[J].Taiwanese Journal of Obstetrics and Gynecology,2019,58( 2):261-265.
[10] 邓茂芳,李奕莲.Cook球囊联合米索前列醇在足月妊娠初产妇引产中的应用效果及对VASA评分的影响[J].河北医学,2019,25(10):1671-1674.