Abstract：Objective: To study and compare the effects of right ventricular middle septum pacing and right ventricular high septum pacing on cardiac function. Methods: From January 2018 to March 2020, 100 patients with complete atrioventricular block undergoing permanent pacemaker implantation in our hospital were included in the study, and were divided into 2 groups with 50 patients in each according to the random number table method. Group A was pacing at the high septum of right ventricle, while group B was pacing at the middle septum of right ventricle. The levels of n-terminal brain natriuretic peptide (NT-proBNP), cardiac color Doppler monitoring index, QRS wave time limit, quality of life score and incidence of adverse cardiac events were compared between the two groups. Results: The levels of NT-proBNP in both groups were significantly lower than those before operation at 3 and 6 months after operation (P<0.05), while the levels of NT-proBNP in Group B were lower than those in Group A at 3 and 6 months after operation (P<0.05). The LVEF, LVEDD, LVESD and LAEF at 3 and 6 months after operation were significantly improved in both groups (P<0.05), while the LVEF and LAEF in group B were higher than those in group a (P<0.05), while the LVEDD and LVESD in group B were lower than those in control group (P<0.05). The QRS wave duration of the two groups at 3 months and 6 months after operation was significantly shorter than that before operation (P<0.05), while the QRS wave duration of Group B was shorter than that of Group A at 3 months and 6 months after operation (P<0.05). The quality of life scores of both groups at 3 and 6 months after operation were significantly lower than those before operation (P<0.05), while the quality of life scores of Group B were lower than those of Group A at 3 and 6 months after operation (P<0.05). Within 6 months after operation, the incidence of adverse cardiac events in group A was 8.00%, while that in group B was 4.00%. There was no significant difference between the two groups (P>0.05). Conclusion: Pacing in the middle septum of right ventricle can improve the cardiac function of patients with permanent pacemaker implantation, which is better than pacing in the high septum of right ventricle, and the risk of adverse cardiac events is not increased, which verifies it’s safety and reliability.
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2021, Vol. 27 
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