Abstract：Objective: To investigate the predictive value of arterial blood flow parameters on threatened abortion in early pregnancy and its relationship with prognosis. Methods: 200 pregnant women with threatened abortion of 5-8 weeks in our hospital from January 2017 to January 2018 were selected as the study group, and 100 normal early intrauterine pregnancy women were selected as the control group. All patients underwent transabdominal ultrasound, uterine artery blood flow parameters were measured, and all pregnant women were followed up to 16 weeks. In the study group, 102 cases of pregnant women with failure of fetal protection were regarded as failure group, 98 cases of pregnant women with success of fetal protection were regarded as success group. The arterial blood flow parameters of the three groups were compared, and the diagnostic value of the arterial blood flow parameters for pregnancy outcome was compared. The serum progesterone and β -hcg levels of the three groups were compared, and the endometrial thickness and the endometrial vascularization parameters of the study group and the control group were compared. Results: There was no significant difference in the peak systolic flow rate of the three groups of pregnant women (P>0.05); the end-diastolic flow rate of the pregnant women in the failed pregnancy loss group was lower than that in the successful pregnancy loss group and the control group, and the pulsation index and resistance index were higher than those in the successful pregnancy loss group and the control group (P<0.05); the end-diastolic flow rate, pulsatility index, and resistance index of the successful fetal pregnancy group were higher than those of the control group (P<0.05). The cut-off value, sensitivity and specificity of uterine artery blood flow parameters have good diagnostic value. The receiver operating curve shows that the peak systolic flow rate/end-diastolic flow rate (S/D), pulsatility index (PI), and resistance index (RI) all have good diagnostic value. The levels of serum progesterone and β-HCG in the successful and unsuccessful groups were lower than those in the control group, and the levels of serum progesterone and β-HCG in the unsuccessful group were lower than those in the unsuccessful group (P<0.05). There was no significant difference in endometrial thickness between the two groups of pregnant women (P>0.05); the endometrial volume, vascular index (VI), blood flow index (FI), and vascular blood flow index (VFI) of the study group were lower than those of the control group (P<0.05). Conclusion: Arterial blood flow parameters have higher predictive value for threatened abortion in early pregnancy, and their sensitivity and specificity are higher, which is beneficial to maternal prognosis and worthy of further clinical promotion.
张礼英, 丁媛媛, 孙雅琴. 动脉血流参数对孕早期先兆流产的预测价值及预后的关系[J]. 河北医学, 2021, 27(5): 827-830.
ZHANG Liying, DING Yuanyuan, SUN Yaqin. Relationship between Arterial Blood Flow Parameters and Prognosis of Threatened Abortion in Early Pregnancy. HeBei Med, 2021, 27(5): 827-830.
2021, Vol. 27 
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