Abstract：Objective: To analyze the effect of laparoscopy on ovarian reserve function and fertility function in tubal pregnancy. Methods: 218 patients with tubal pregnancy in our hospital were retrospectively studied. According to different treatments, they were divided into the conservative group (87 cases), the resection group (89 cases), and the retention group (42 cases). After treatment, sex hormone levels, ovarian function parameters, and the repregnancy status of the 3 groups were compared. Results: There were significant differences in the content of sex hormone (FSH, E2, LH, progesterone) and the level of ovarian function (ovarian sectional area, number of sinusoid follicles, PSV, EDV) among the three groups after treatment (P<0.05). Pair comparison showed that the content of three sex hormones (FSH, E2 and LH) in the retention group was significantly lower than that in the conservative group and the resection group, and the progesterone level and various ovarian function parameters in the retention group were significantly higher than that in the conservative group and the resection group, with statistically significant differences between the two groups (P<0.05). Compared at different time points, the E2, progesterone sex hormone levels and various ovarian function parameters of the three groups showed a significant downward trend with time migration, while the FSH and LH sex hormone levels increased significantly. The incidence of non-pregnancy in the conservative group (39.08%), the excision group (41.57%) and the retention group (23.80%) was statistically significant (P<0.05). The incidence of intrauterine pregnancy in the conservative group (32.18%), the excision group (28.09%), and the retention group (26.19%) had statistically significant differences (P<0.05). Conclusion: Compared with other commonly used therapies, laparoscopic tubal preservation surgery in patients with tubal pregnancy can better preserve fertility and has better ovarian reserve function.
张进, 陈梅, 徐秀兰. 腹腔镜保留输卵管术对输卵管妊娠患者卵巢储备功能及生育功能的影响[J]. 河北医学, 2021, 27(2): 264-268.
ZHANG Jin, CHEN Mei, XU Xiulan. Effect of Laparoscopic Oviduct Sparing Surgery on Ovarian Reserve Function and Re-productive Function in Patients with Tubal Pregnancy. HeBei Med, 2021, 27(2): 264-268.
[1] 王婉童,马晓欣.不同腹腔镜手术方式治疗输卵管积水对卵巢储备功能及IVF-ET妊娠结局的影响[J].中国实用妇科与产科杂志,2019,35(7):820~822. [2] 赵惠杰.腹腔镜下卵巢囊肿蒂扭转保留卵巢术对患者血清FSH水平及卵巢储备功能的影响[J].河南医学研究,2017,26(19):3573~3574. [3] Bayoumi YA,Dakhly DM,Bassiouny YA,et al. Addition of growth hormone to the microflare stimulation protocol among women with poor ovarian response[J]. Int Gynaecol Obstet,2015,131(3):305~308. [4] Tartagni M,Cicinelli MV,Baldini D,et al. Dehydroepiandrosterone decreases the age-related decline of the in vitro fertilization outcome in women younger than 40 years old[J]. Reprod Biol Endocrinol,2015,13(1):14. [5] 周一帆,王睿,王曼,等.腹腔镜保留输卵管术对输卵管妊娠患者卵巢储备功能及生育功能的影响[J].中国妇幼保健,2017,32(10):2231~2233. [6] Pires JA,Chilliard Y,Delavaud C,et al. Physiological adaptations and ovarian cyclicity of Holstein and Montbeliarde cows under two low-input production systems[J]. Animal,2015,9(12):1986~1995. [7] Gleicher N,Vega MV,Darmon SK,et al. Live-birth rates in very poor prognosis patients,who are defined as poor responders under the Bologna criteria,with nonelective single embryo, two-embryo,and three or more embryos transferred[J]. Fertil Steril,2015,104(6):1435~1441. [8] 张岭,徐维海,黄琼晓,等.卵巢储备功能减退患者中GnRHa扳机方案的胚胎培养结局分析[J].中国临床药理学与治疗学,2019,24(7):799~804. [9] 陈斌.输卵管妊娠不同治疗方式对患者生育功能的影响[J].实用临床医学,2016,17(6):53~55. [10] 孙恒,王佳,李小娟,等.腹腔镜下不同术式对输卵管妊娠治疗后生育功能的影响[J].中国妇产科临床杂志,2019,20(3):262~263. [11] 李佳琦,吴晓兰.腹腔镜输卵管修补及功能再造在输卵管妊娠患者保留生育功能中的应用研究[J].陕西医学杂志,2018,47(11):1420~1423.
2021, Vol. 27 
冀公网安备13080202000677号