Abstract：Objective: To study the correlation between serum soluble interleukin-2 receptor (SIL-2R) level and T lymphocyte subsets levels in secretory otitis media (SOM). Methods: A total of 235 patients with SOM admitted to the hospital from March 2015 to December 2019 were selected as observation group. Another 100 healthy people who underwent physical examination in our hospital at the same time period were selected as control group. The levels of SIL-2R and T lymphocyte subsets-related indexes were measured in the two groups. The correlation between SIL-2R and T lymphocyte subsets was analyzed by Pearson correlation. Results: The levels of CD3, CD4 and CD4 / CD8 in the observation group were significantly lower than those in the control group (P<0.05), and the level of CD8 in the observation group was significantly higher than that in the control group (P<0.05). The level of SIL-2R in the observation group was significantly higher than that in the control group (P<0.05); the level of serum SIL-2R was significantly negatively correlated with CD3, CD4, CD4 / CD8 (P<0.05), and positively correlated with CD8 (P<0.05). Conclusions: There is a certain correlation between SIL-2R and T lymphocyte subsets levels.
陈璇, 历东东, 石燕. 分泌性中耳炎血清SIL-2R水平 T淋巴细胞亚群水平检测及其相关性研究[J]. 河北医学, 2020, 26(10): 1623-1625.
CHEN Xuan, LI Dongdong, SHI Yan. Detection of Serum SIL-2R Level and T lymphocyte Subsets Levels and The Correlation in Secretory Otitis Media. HeBei Med, 2020, 26(10): 1623-1625.
2020, Vol. 26 
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